BIO552 - RECENT TRENDS IN SMALL RNA BIOLOGY - M.Sc. Biotechnology & Microbiology - Semester 3
COURSE NAME: Recent Trends in Small RNA Biology TYPE: Elective PROGRAM: M.Sc. Biotechnology / M.Sc. Microbiology SEMESTER: Three CREDITS: Three INSTRUCTOR: Harikrishnan SSYLLABUS:
The discovery of RNA interference - Introduction to microRNA and the Classic Works of Ambros and Ruvkun - Endogenous miRNA - Posttranscriptional Processing of microRNA - microRNA:Target Pairing and RISC Function - microRNA Target Genomics (with introduction to bioinformatic tools) - Harnessing RNAi as a tool - microRNA Function in Vertebrate Development - miRNAs in cancer: tumor suppressors and oncogenes - Small Bacterial RNAs –CRISPR - piRNAs - SnoRNAs - lincRNAs - miRNAs and diseases - A case study of miRNA function in human diseaseREFERENCES:
- MicroRNAs -From Basic Science to Disease - Krishnarao Appasani- Cambridge University Press
- RNAi: A Guide to Gene Silencing - Gregory J. Hannon - Cold Spring Harbor Laboratory Press
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