Docking studies are computational techniques for the exploration of the possible binding modes of a substrate to a given receptor, enzyme or other binding site. The application of computational methods to study the formation of intermolecular complexes has been the subject of intensive research during the last decade.
Research Projects @ Phytochemistry Labs
Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis.diversity-oriented-synthesis-applications-to-flavonols-flavones-isoflavones-and-biflavones
After broad separation of tannins as lead complex from the SBT extract , flavonoid glycosides (in the supernatant) were subjected to column chromatography using SiO2 and LH-20. Partially purified fractions were put for preparative HPLC and glycosides were isolated.molecular-structural-studies-of-complex-natural-products-by-lcms-and-uv-spectrophotometry
In the Phytochemistry laboratory, development, analysis, and optimization of technical processes for target dependent bioactive compound isolations and assays are carried out. A brief account is given below.process-development-for-isolation-and-characterization-of-phytochemicals
Seabuckthorn (SBT), (Hippophae L.) are deciduous shrubs in the genus Hippophae, family Elaeagnaceae. In addition to the nutritionally active constituents, many clinically important activities of seabuckthorn (SBT), such as beneficial effects on skin, cardiovascular diseases, diabetes, wound healing, cancer chemopreventive action, antiviral activity, sun screen and radioprotection have been established.seabuckthorn-a-repository-of-bioactive-phytochemicals
There are a wide range of underutilized plants with well known nutritional and medicinal properties. They have the potential for further promotion as they are locally available or are byproducts or waste materials. They are culturally accepted and often well established component of life systems and diets. Some of the isolated phytochemicals from them have commercial value.