COURSE SUMMARY
Course Title: 
Intelligence of Biological Systems 2
Course Code: 
19BIO112
Year Taught: 
2019
Semester: 
2
Type: 
Subject Core
Degree: 
Undergraduate (UG)
School: 
School of Engineering
Campus: 
Bengaluru
Coimbatore
Amritapuri

'Intelligence of Biological Systems 2' is a course offered in the second semester of  B. Tech. in Computer Science and Engineering (Artificial Intelligence) program at the School of Engineering, Amrita Vishwa Vidyapeetham.

Course Objectives

The course will aim at introducing the concepts pertaining to DNA replication and will equip the students to explore the question where in the genome does the DNA replication will begin. Further it will motivate the students to investigate the origin of various rhythms observed in human body such as circadian rhythm and how they are encoded in the DNA

Course Outcomes

CO1 To investigate DNA replication.
CO2 To investigate the encodings in DNA to maintain various rhythms associated with the body.
CO3 To introduce state of the art computational algorithms to understand DNA encodings.

 

  PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PO11 PO12
CO1 2 3 2 2 3 2 2   3 2 3 3
CO2 1 3 3 2 3 2 2   3 2 3 3
CO3 1 2 3 3 3 2 2   3 2 3 3

Course Evaluation Pattern:

Internal – 75%

  • Assignments – 50% (20 assignments with equal credit)
  • Quiz- 25% (5 Quizzes with equal credit)

External – 25%

  • Project – 25%

DNA replication – genome - hidden messages in the genome - Python Programming and packages for Bioinformatics - Finding Replication Origins - DnaA boxes - Counting words - The Frequent Words Problem - Frequent words in Vibrio cholera – encodings in DNA to maintain circadian rhythm – Hunting for Regulatory Motifs - Motif Finding - Scoring Motifs - Greedy Motif Search - Randomized Motif Search - Gibbs Sampling.

  1. Philip Compeau and PavelPevzener, Finding Hidden Messages in DNA, Active Learning Publishers 2015.