Dr. B. Ranganathan
Dr. B. Ranganathan joined as an Associate Professor in the Department of Pharmaceutical Chemistry at Amrita in May 2011. He received his Ph. D. in Medicinal Chemistry from the University of Minnesota, United States. He did a one-year postdoctoral fellowship in Nuclear Medicine from Johns Hopkins University, Baltimore. He has his B.Pharm (Hons.) from Birla Institute of Technology and Science, Pilani and later obtained his M. S. in Pharmaceutical Chemistry from Fairleigh Dickinson University, New Jersey.
After returning from his higher education in the United States, he tried his hands in the industry for about a year wherein he worked as Assistant General Manager (R&D) at Porus Labs Pvt. Ltd., Hyderabad. In this capacity, his role was to lead a team of chemists towards the route optimization of certain Active Pharmaceutical Ingredients (APIs) as per the clients’ specifications. The clients often included major pharmaceutical companies like Reddy’s Labs, Hetero and Sun Pharma among others.
Dr. Ranganathan’s areas of interest broadly include optimization of synthetic methodology and development of small molecules as diverse therapeutic agents. Currently, he is involved with exploring the chalcones as a privileged scaffold for different pharmacological activities. A number of synthetic chalcones have been synthesized by his students and testing is underway for their possible role as anti-inflammatory and anticancer agents, antioxidants and antimicrobial compounds. It is hoped that this medicinal chemistry approach will pave the way for systematic elucidation of structure-activity relationships.
In his capacity as guide, he is mentoring B. Pharm. and M. Pharm. thesis projects some of which include:
- Chemical Characterization and Toxicological Risk Assessment of Selected Smokeless Tobacco Products
- Towards the Structure-Activity Relationships of Anti-inflammatory Chalcones
- Estimating the Antioxidant Potential of Rationally Designed Synthetic Chalcones
- Synthesis and Preliminary Evaluation of Ring-A Monosubstituted Chalcones as Potential Anti-inflammatory Agents