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Dr. Manisha Nidhar

Assistant Professor Dept. of Pharmaceutical Chemistry, School of Pharmacy, Kochi

Qualification: M. Pharm., Ph.D
manishanidhar@yahoo.com
Research Interest: Computer-aided drug design, Synthesis of bioactive molecules as antidiabetic agents

Bio

Dr. Manisha Nidhar is an Assistant Professor at the Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Kochi, India. She completed her B. Pharm in the year 2011 from IPS College of Pharmacy, Shivpuri Link Road, Gwalior (M.P.). She obtained M. Pharm in Pharmaceutical chemistry from School of pharmacy, Devi Ahilya Vishwavidyalaya, Indore Purge from cachein 2013 and Ph.D. in Pharmaceutical chemistry from Department of Chemistry, Banaras Hindu University, Varanasi, Uttar Pradesh, in 2022.
Dr. Manisha Nidhar has several publications in peer reviewed journals and has presented his research work in national and international conferences. Her research areas of focus are in computer-aided drug design and synthesis of novel bioactive molecules as antidiabetic agents and DPP-4 Inhibitors.

  • Participated in the one-day national seminar on “Screening Strategies in Drug discovery”.
  • Participated in the national seminar on the scope & potentials after pharmacy graduation.
  •  Participated in one-day workshop on “Current opportunities and challenges in clinical research”.
  •  Participated in Indian pharmaceutical association, Pharma meet-2013.
  • Qualified in Graduate Pharmacy Aptitude Test (GPAT) in 2011.
Publications

Journal Article

Year : 2022

Design, synthesis, molecular modeling of heterodimer and inhibitors of α-amylase as hypoglycemic agents

Cite this Research Publication : Manisha Nidhar, Ved Prakash Singh, Pratima Yadav, Ranjeet Kumar, Priyanka Sonker, and Ashish Kumar Tewari, Design, synthesis, molecular modeling of heterodimer and inhibitors of α-amylase as hypoglycemic agents, Molecular Diversity, 2022, 10.1007/s11030-022-10414-8.

Publisher : Molecular Diversity, Springer science

Year : 2022

Click inspired novel pyrazole-triazole-persulfonimide & pyrazole-triazole-aryl derivatives; Design, synthesis, DPP-4 inhibitor with potential anti-diabetic agents

Cite this Research Publication : Manisha Nidhar, Shaziya Khanam, Priyanka Sonker, Priya Gupta, Archisman Mahapatra, Swaraj Patil, Brijesh Kumar Yadav, Rahul Kumar Singh, Ashish Kumar Tewari, Click inspired novel pyrazole-triazole-persulfonimide & pyrazole-triazole-aryl derivatives; Design, synthesis, DPP-4 inhibitor with potential anti-diabetic agents, Bioorganic Chemistry, 120, 2022, https://doi.org/10.1016/j.bioorg.2021. 105586

Publisher : Bioorganic Chemistry, Elsevier

Year : 2022

Lead modification on sitagliptin via computational studies; Synthesis, biological evaluation of pyrazole containing β-amino carbonyls for the treatment of type-2 diabetes.

Cite this Research Publication : Manisha Nidhar, Vipin Kumar, Archisman Mahapatra, Priya Gupta, Priyanka Sonker, Priyanka Yadav, Shweta Mishra, Rahul Kumar Singh, and Ashish Kumar Tewari, Lead modification on sitagliptin via computational studies; Synthesis, biological evaluation of pyrazole containing β-amino carbonyls for the treatment of type-2 diabetes. Chemical Biology & Drug Design, 2022, 1– 12. https://doi.org/10.1111/cbdd.14157

Publisher : Chemical Biology & Drug Design

Year : 2022

Novel pyrimido-pyridazine derivatives: design, synthesis, anticancer evaluation and in silico studies

Cite this Research Publication : Priyanka Sonker, Mamata Singh, Manisha Nidhar, Vishal Prasad Sharma, Priyanka Yadav, Rashmi Singh, Biplob Koch, and Ashish Kumar Tewari, Novel pyrimido-pyridazine derivatives: design, synthesis, anticancer evaluation and in silico studies, Future Medicinal Chemistry, 2022, https://doi.org/10.4155/fmc-2022-0199.

Publisher : Future Medicinal Chemistry

Year : 2022

Design, synthesis, and in-silico & in vitro enzymatic inhibition assays of pyrazole-chalcone derivatives as dual inhibitors of α-amylase & DPP-4 enzyme

Cite this Research Publication : Manisha Nidhar, Priyanka Sonker, Vishal Prasad Sharma, Sanjay Kumar, and Ashish Kumar Tewari, Design, synthesis, and in-silico & in vitro enzymatic inhibition assays of pyrazole-chalcone derivatives as dual inhibitors of α-amylase & DPP-4 enzyme chemical papers 2022. https://doi.org/10.1007/s11696-021-01985

Publisher : Springer International Publishing

Year : 2022

Ligand-based designing of DPP-4 inhibitors via hybridization; synthesis, docking, and biological evaluation of pyridazine-acetohydrazides

Cite this Research Publication : Manisha Nidhar, Vipin Kumar, Archisman Mahapatra, Priya Gupta, Brijesh Kumar Yadav, Rahul Kumar Singh, and Ashish Kumar Tewari, Ligand-based designing of DPP-4 inhibitors via hybridization; synthesis, docking, and biological evaluation of pyridazine-acetohydrazides, Molecular Diversity (2022). https://doi.org/10.1007/s 11030-022-10577-4.

Publisher : Molecular Diversity, Springer science

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