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Dr. Manzoor K.

Professor, Amrita School of Nanosciences and Molecular Medicine, Kochi

Qualification: Ph.D
manzoork@aims.amrita.edu

Bio

Dr. Manzoor Koyakutty currently serves as Professor, Cancer Nanomedicine & Immunotherapeutics Group, Amrita Center for Nanosciences and Molecular Medicine, Cochin, India. He specializes in the area of Cancer nanomedicine & Immunotherapeutics. Dr. Manzoor joined ACNS during June 2007 after 9 years of service as Staff-Scientist at the Defence Research and Development Organization (DRDO), Government of India. During this tenure, he completed Ph. D. in Physics (Nanoscience) from DRDO (JNVU, Jodhpur) under the guidance of Dr. S. R. Vadera, Director, DRDO and Prof. T. R. N. Kutty, Indian Institute of Science, Bangalore. After shifting to Amrita, Dr. Manzoor’s team focused on the area of cancer-nanomedicine and developed many novel nano-systems to interfere with the complex biology of cancer. With the emergence of cancer-immunotherapy, his team also work on activating the immune system against cancer using novel nano-immunomedicines. Specific areas of research include: nanomedicines for drug -radiation resistant cancer and cancer stem cells, brain implantable nanomedicine for prolonged drug-delivery, nanoparticle-based image guided radio-wave therapy and photodynamic therapy, cancer immunotherapy using dendritic cells (DC), neo-mRNA nano-vaccines, Raman spectral imaging of cancer, application of artificial intelligence (IA) in nanomedicine and immunotherapy. He has 32 international patents (10 issued in USA/ Japan/China/Europe) and published more than 65 peer reviewed research papers in nanomedicine. Three IPs are licenced to pharma companies for commercial development. He serves as Associate Editor of the Journal: Precision Nanomedicine (European Foundation for Clinical Nanomedicine-CLINAM). He also served in the editorial board member of the journal Nanomedicine: NBM (Elsevier). He is an expert member in ‘Translational Nano-Biotechnology’ Task force, Dept. of Biotechnology, Govt of India. He is a co-founder of the bio-pharma start-up company M/s LuxMatra Innovations Pvt. Ltd, C-Camp, Bangalore.

Awards / Recognitions

  • 2003 DRDO Laboratory Scientist of the Year
  • 2004 DRDO Young Scientist Award
  • 2006 DRDO Technology Developer Award
  • 2003 National Science Day Award for best scientific publication, DRDO
  • 2004 National Science Day Award for best scientific publication, DRDO
  • 2005 National Science Day Award for best scientific publication, DRDO
  • 2006 National Science Day Award for best scientific publication, DRDO
  • 2007 Marie Curie International Incoming Fellowship (IIF), FP-7
  • 2013 Best Reviewer award, Journal Nanomedicine: NBM
  • 2014 Taskforce Member: RNAi Program, Govt of India
  • 2014 Taskforce Member: NanoBiotechnology Program, Govt of India
  • 2017 Fellow of National Academy of Sciences, FNASc (Biological Sciences)
  • 2018 Taskforce Member: Translational Nanomedicine Program, DBT, Govt of India
  • 2018 Assoc. Editor, Journal Precision nanomedicine (Eur. Found. for Clinical Nanomedicine)

Research Projects

  • Nano-fiber brain implant for prolonged and localized delivery of anti-glioma drugs: Funding by TPF-Nanomission, Dept of Sci & Tech (DST), India
  • Nanoparticle based gene editing using CRISPR-Cas 9, TPF-Nanomission, DST, India; Collaborator: Dr Lekshmi Sumitra, ACNS
  • Translational Development of Protein-Sorafenib nanomedicine, Dept of Biotechnology (DBT)
  • Translational development of nCP nanotheranostic agent, Dept of Biotechnology (DBT)
  • Nano-Photomedicine for Glioblastoma, M/s Lead Invent Pharma, USA,
  • Indo-Singapore Grant on stem cell tracking using nCP:Fe contrast agent (DBT), with Prof. Kishore Bhakoo, SBIC, Singapore
  • Portable Cancer Raman Device (DBT) : Dept of Biotechnology (DBT) with Dr Girish C M
  • Gamma Delta T Cell cancer immunotherapy, as Co-PI with Dr Anusha, SERB-DST
  • Nanoengineered autoantigens for the prevention and treatment of autoimmunity, Indo-Australian project with Dr K Menon and Claud Bernard, Monash University:
  • Controlled release of human hormones, M/S Function Promoting Technologies (FPT), Cambridge, USA

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Publications

Journal Article

Year : 2021

Magnetic 3D scaffold: A theranostic tool for tissue regeneration and non-invasive imaging in vivo

Cite this Research Publication : K. Meethaleve Sajesh, Anusha Ashokan, Gowd, G. Siddaraman, Dr. Manzoor K., Unni, A. K. K., and Shantikumar V Nair, “Magnetic 3D scaffold: A theranostic tool for tissue regeneration and non-invasive imaging in vivo.”, Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 18, pp. 179-188, 2019.

Publisher : Nanomedicine: Nanotechnology, Biology, and Medicine

Year : 2021

Cancer nanomedicine developed from total human serum: a novel approach for making personalized nanomedicine.

Cite this Research Publication : Jyotsna Thayath, Dr. Pavithran K., Shantikumar V Nair, and Dr. Manzoor K., “Cancer nanomedicine developed from total human serum: a novel approach for making personalized nanomedicine.”, Nanomedicine, vol. 16, no. 12, pp. 997-1015, 2021.

Publisher : Nanomedicine

Year : 2021

Low PDL1 Expression in Tumour Infiltrating Lymphocytes Predicts Local Recurrence in Oral Squamous Cell Carcinoma.

Cite this Research Publication : Narayana Subramaniam, Ajit Nambiar, Sujan Dhar, Krishnakumar Thankappan, Dr. Manzoor K., Deepak Balasubramanian, Manjula Das, and Subramania Iyer, “Low PDL1 Expression in Tumour Infiltrating Lymphocytes Predicts Local Recurrence in Oral Squamous Cell Carcinoma.”, Indian Journal of Surgical Oncology, vol. 12, no. 2, pp. 408-414, 2021.

Publisher : Indian Journal of Surgical Oncology

Year : 2018

Computational Simulations and Experimental Validation of Structure- Physicochemical Properties of Pristine and Functionalized Graphene: Implications for Adverse Effects on p53 Mediated DNA Damage Response

Cite this Research Publication : F. Basheer, Melge, A. R., Sasidharan, A., Shantikumar V Nair, Dr. Manzoor K., and Dr. Gopi Mohan C., “Computational Simulations and Experimental Validation of Structure- Physicochemical Properties of Pristine and Functionalized Graphene: Implications for Adverse Effects on p53 Mediated DNA Damage Response”, International Journal of Biological Macromolecules, vol. 110, pp. 540-549, 2018

Publisher : International Journal of Biological Macromolecules,

Year : 2018

Predictive Models for Designing Potent Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia for Understanding its Molecular Mechanism of Resistance by Molecular Docking and Dynamics Simulations

Cite this Research Publication : A. R. Melge, Kumar, L. G., Pavithran, K., Shantikumar V Nair, Dr. Manzoor K., and Dr. Gopi Mohan C., “Predictive Models for Designing Potent Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia for Understanding its Molecular Mechanism of Resistance by Molecular Docking and Dynamics Simulations”, Journal of Biomolecular Structure and Dynamics, 2018.

Publisher : Journal of Biomolecular Structure and Dynamics, Taylor and Francis Ltd.

Year : 2017

Biomineral Nano-Theranostic Agent for Magnetic Resonance Image Guided, Augmented Radiofrequency Ablation of Liver Tumor.

Cite this Research Publication : A. Ashokan, Somasundaram, V. Harish, Gowd, G. Siddaraman, Anna, I. M., Malarvizhi, G. L., Sridharan, B., Jobanputra, R. B., Peethambaran, R., Unni, A. K. K., Shantikumar V Nair, and Dr. Manzoor K., “Biomineral Nano-Theranostic Agent for Magnetic Resonance Image Guided, Augmented Radiofrequency Ablation of Liver Tumor.”, Scientific Reports, vol. 7, no. 1, p. 14481, 2017.

Publisher : Scientific Reports

Year : 2017

Bioinspired Composite Matrix Containing Hydroxyapatite-Silica Core-Shell Nanorods for Bone Tissue Engineering

Cite this Research Publication : A. Anitha, Dr. Deepthy Menon, Sivanarayanan, T. B., Dr. Manzoor K., Mohan, C. C., Shantikumar V Nair, and Nair, M. B., “Bioinspired Composite Matrix Containing Hydroxyapatite-Silica Core-Shell Nanorods for Bone Tissue Engineering”, ACS Applied Materials and Interfaces, vol. 9, no. 32, pp. 26707-26718, 2017.

Publisher : ACS Applied Materials and Interfaces,

Year : 2016

Biodegradable Radiofrequency Responsive Nanoparticles for Augmented Thermal Ablation Combined with Triggered Drug Release in Liver Tumors

Cite this Research Publication : V. H. Somasundaram, Pillai, R., Malarvizhi, G., Anusha Ashokan, Gowd, S., Peethambaran, R., Palaniswamy, S., Unni, A. K. K., Shantikumar V Nair, and Dr. Manzoor K., “Biodegradable Radiofrequency Responsive Nanoparticles for Augmented Thermal Ablation Combined with Triggered Drug Release in Liver Tumors”, ACS Biomaterials Science and Engineering, vol. 2, pp. 768-779, 2016.

Publisher : ACS Biomaterials Science and Engineering, American Chemical Society.

Year : 2015

Radiofrequency Ablation of Drug-Resistant Cancer Cells Using Molecularly Targeted Carboxyl-Functionalized Biodegradable Graphene

Cite this Research Publication : A. Sasidharan, Sivaram, A. J., Retnakumari, A. P., Chandran, P., Malarvizhi, G. Loghanatha, Shantikumar V Nair, and Dr. Manzoor K., “Radiofrequency Ablation of Drug-Resistant Cancer Cells Using Molecularly Targeted Carboxyl-Functionalized Biodegradable Graphene”, Advanced Healthcare Materials, vol. 4, pp. 679-684, 2015.

Publisher : Advanced Healthcare Materials

Year : 2015

Manganese doped Nano-bioactive Glass for Magnetic Resonance Imaging

Cite this Research Publication : N. Vadera, Anusha Ashokan, Genekehal S. Gowd, Sajesh, K. M., Chauhan, R. P., Dr. Jayakumar Rangasamy, Shantikumar V Nair, and Dr. Manzoor K., “Manganese doped Nano-bioactive Glass for Magnetic Resonance Imaging”, Materials Letters, vol. 160, pp. 335 - 338, 2015.

Publisher : Materials Letters

Year : 2015

Protein Nanomedicine Exerts Cytotoxicity toward CD34+ CD38– CD123+ Leukemic Stem Cells

Cite this Research Publication : P. Chandran, Pavithran, K., Sidharthan, N., Sasidharan, A., Shantikumar V Nair, and Dr. Manzoor K., “Protein Nanomedicine Exerts Cytotoxicity toward CD34+ CD38– CD123+ Leukemic Stem Cells”, ACS Biomaterials Science & Engineering, vol. 1, pp. 1194-1199, 2015.

Publisher : ACS Biomaterials Science & Engineering,

Year : 2015

Transferrin-Conjugated Biodegradable Graphene for Targeted Radiofrequency Ablation of Hepatocellular Carcinoma

Cite this Research Publication : Dr. Manzoor K., D, B., Girish C. M., A, S., and S, N., “Transferrin-Conjugated Biodegradable Graphene for Targeted Radiofrequency Ablation of Hepatocellular Carcinoma”, ACS Biomaterials Science and Engineering, vol. 1, no. 12, pp. 1211-9, 2015.

Publisher : ACS Biomaterials Science and Engineering

Year : 2015

Comparative in Vivo Toxicity, Organ Biodistribution and Immune Response of Pristine, Carboxylated and PEGylated Few-layer Graphene Sheets in Swiss Albino Mice: A three month study

Cite this Research Publication : Abhilash Sasidharan, Siddharth Swaroop, Chaitanya K. Koduri, Girish C. M., Parwathy Chandran, L.S. Panchakarla, Vijay H. Somasundaram, Genekehal S. Gowd, Shantikumar V Nair, and Dr. Manzoor K., “Comparative in Vivo Toxicity, Organ Biodistribution and Immune Response of Pristine, Carboxylated and PEGylated Few-layer Graphene Sheets in Swiss Albino Mice: A three month study”, Carbon, vol. 95, pp. 511 - 524, 2015.

Publisher : Carbon

Year : 2014

Efficacy versus Toxicity – The Yin and Yang in translating nanomedicines,

Cite this Research Publication : Dr. Sahadev Shankarappa, Dr. Manzoor K., and Shantikumar V Nair, “Efficacy versus Toxicity - The Yin and Yang in translating nanomedicines,”, Nanomaterials and Nanotechnology, vol. 4, no. 23, 2014.

Publisher : Nanomaterials and Nanotechnology,

Year : 2013, 2014

Epigenetics targeted protein-vorinostat nanomedicine inducing apoptosis in heterogeneous population of primary acute myeloid leukemia cells including refractory and relapsed cases

Cite this Research Publication : Pa Chandran, Kavalakatt, Aa, Malarvizhi, G. La, Vasanthakumari, D. R. V. Na, Retnakumari, A. Pa, Sidharthan, Nb, Pavithran, Kb, Nair, Sa, and Dr. Manzoor K., “Epigenetics targeted protein-vorinostat nanomedicine inducing apoptosis in heterogeneous population of primary acute myeloid leukemia cells including refractory and relapsed cases”, Nanomedicine: Nanotechnology, Biology, and Medicine, 2013.

Publisher : Nanomedicine: Nanotechnology, Biology, and Medicine

Year : 2014

Transferrin Targeted Core-shell Nanomedicine for Combinatorial Delivery of Doxorubicin and Sorafenib Against Hepatocellular Carcinoma

Cite this Research Publication : G. L. Malarvizhi, Retnakumari, A. P., Nair, S., and Dr. Manzoor K., “Transferrin Targeted Core-shell Nanomedicine for Combinatorial Delivery of Doxorubicin and Sorafenib Against Hepatocellular Carcinoma”, Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 10, pp. 1649-1659, 2014.

Publisher : Nanomedicine: Nanotechnology, Biology, and Medicine

Year : 2013

Simultaneous Inhibition of Aberrant Cancer Kinome Using Rationally Designed Polymer-Protein Core-shell Nanomedicine

Cite this Research Publication : P. Chandran, Gupta, N., Retnakumari, A. P., Malarvizhi, G. L., Keechilat, P., Nair, S., and Dr. Manzoor K., “Simultaneous Inhibition of Aberrant Cancer Kinome Using Rationally Designed Polymer-Protein Core-shell Nanomedicine”, Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 9, pp. 1317-1327, 2013.

Publisher : Nanomedicine: Nanotechnology, Biology, and Medicine

Year : 2013

Confocal Raman Imaging Study Showing Macrophage Mediated Biodegradation of Graphene in Vivo

Cite this Research Publication : A. Sasidharan, Girish C. M., Gowd, G. S., Nair, S., and Dr. Manzoor K., “Confocal Raman Imaging Study Showing Macrophage Mediated Biodegradation of Graphene in Vivo”, Advanced Healthcare Materials, vol. 2, pp. 1489-1500, 2013.

Publisher : Advanced Healthcare Materials

Year : 2013

Multifunctional Calcium Phosphate Nano-contrast agent for Combined Nuclear, Magnetic and Near-Infrared Invivo Imaging

Cite this Research Publication : Anusha Ashokan, Gowd, G. S., Somasundaram, V. H., Bhupathi, A., Peethambaran, R., Unni, A. K. K., ,, Shantikumar V Nair, and Dr. Manzoor K., “Multifunctional Calcium Phosphate Nano-contrast agent for Combined Nuclear, Magnetic and Near-Infrared Invivo Imaging”, Biomaterials, vol. 34, pp. 7143-7157, 2013.

Publisher : Biomaterials

Year : 2013, 2014

Epigenetics targeted protein-vorinostat nanomedicine inducing apoptosis in heterogeneous population of primary acute myeloid leukemia cells including refractory and relapsed cases

Cite this Research Publication : Pa Chandran, Kavalakatt, Aa, Malarvizhi, G. La, Vasanthakumari, D. R. V. Na, Retnakumari, A. Pa, Sidharthan, Nb, Pavithran, Kb, Nair, Sa, and Dr. Manzoor K., “Epigenetics targeted protein-vorinostat nanomedicine inducing apoptosis in heterogeneous population of primary acute myeloid leukemia cells including refractory and relapsed cases”, Nanomedicine: Nanotechnology, Biology, and Medicine, 2013.

Publisher : Nanomedicine: Nanotechnology, Biology, and Medicine

Year : 2012

Development and Haematotoxicological Evaluation of Doped Hydroxyapatite based Multimodal Nanocontrast Agent for Near-infrared, Magnetic Resonance and X-ray Contrast Imaging

Cite this Research Publication : Anusha Ashokan, Parwathy Chandran, Sadanandan, A. R., Chaitanya K. Koduri, Retnakumari, A. P., Menon, D., Shantikumar V Nair, and Dr. Manzoor K., “Development and Haematotoxicological Evaluation of Doped Hydroxyapatite based Multimodal Nanocontrast Agent for Near-infrared, Magnetic Resonance and X-ray Contrast Imaging”, Nanotoxicology, vol. 6, pp. 652-666, 2012.

Publisher : Nanotoxicology, Taylor & Francis,

Year : 2012

Rationally Designed Aberrant Kinase-Targeted Endogenous Protein Nanomedicine Against Oncogene Mutated/Amplified Refractory Chronic Myeloid Leukemia

Cite this Research Publication : A. P. Retnakumari, Hanumanthu, P. L., Malarvizhi, G. L., Prabhu, R., Sidharthan, N., Thampi, M. V., Dr. Deepthy Menon, Mony, U., Krishnakumar N. Menon, Keechilat, P., Nair, S., and Dr. Manzoor K., “Rationally Designed Aberrant Kinase-Targeted Endogenous Protein Nanomedicine Against Oncogene Mutated/Amplified Refractory Chronic Myeloid Leukemia”, Molecular Pharmaceutics, vol. 9, pp. 3062-3078, 2012.

Publisher : Molecular Pharmaceutics

Year : 2012

Hemocompatibility and macrophage response of pristine and functionalized graphene.

Cite this Research Publication : A. Sasidharan, Panchakarla, L. S., Sadanandan, A. R., Ashokan, A., Chandran, P., Girish, C. Madathil, Menon, D., Nair, S. V., Rao, C. N. R., and Koyakutty, M., “Hemocompatibility and macrophage response of pristine and functionalized graphene.”, Small, vol. 8, no. 8, pp. 1251-63, 2012.

Publisher : Small

Year : 2012

In Vitro Targeted Imaging and Delivery of Camptothecin using Cetuximab-Conjugated Multifunctional PLGA-ZnS Nanoparticles

Cite this Research Publication : V. G. Deepagan, Sarmento, B., Dr. Deepthy Menon, Nascimento, A., Jayasree, A., Sreeranganathan, M., Dr. Manzoor K., Nair, S. V., and Dr. Jayakumar Rangasamy, “In Vitro Targeted Imaging and Delivery of Camptothecin using Cetuximab-Conjugated Multifunctional PLGA-ZnS Nanoparticles”, Nanomedicine, vol. 7, pp. 507-519, 2012.

Publisher : NanomedicineNanomedicine,

Year : 2011

Highly Biocompatible TiO2:Gd3+ Nano-contrast Agent with Enhanced Longitudinal Relaxivity for Targeted Cancer Imaging

Cite this Research Publication : P. Chandran, Abhilash Sasidharan, Anusha Ashokan, Dr. Deepthy Menon, Shantikumar V Nair, and Dr. Manzoor K., “Highly Biocompatible TiO2:Gd3+ Nano-contrast Agent with Enhanced Longitudinal Relaxivity for Targeted Cancer Imaging”, Nanoscale, vol. 3, pp. 4150-4161, 2011.

Publisher : Nanoscale

Year : 2011

Rapid Dissolution of ZnO Nanocrystals in Acidic Cancer Microenvironment Leading to Preferential Apoptosis

Cite this Research Publication : Abhilash Sasidharan, Chandran, P., Dr. Deepthy Menon, Raman, S., Nair, S., and Dr. Manzoor K., “Rapid Dissolution of ZnO Nanocrystals in Acidic Cancer Microenvironment Leading to Preferential Apoptosis”, Nanoscale, vol. 3, pp. 3657-3669, 2011.

Publisher : Nanoscale

Year : 2010

A Molecular Receptor Targeted, Hydroxyapatite Nanocrystal based Multi-modal Contrast Agent

Cite this Research Publication : Anusha Ashokan, Dr. Deepthy Menon, Nair, S., and Dr. Manzoor K., “A Molecular Receptor Targeted, Hydroxyapatite Nanocrystal based Multi-modal Contrast Agent”, Biomaterials, vol. 31, pp. 2606-2616, 2010.

Publisher : Biomaterials

Year : 2010

Folate Receptor Targeted, Rare-earth Oxide Nanocrystals for Bi-modal Fluorescence and Magnetic Imaging of Cancer Cells

Cite this Research Publication : S. Setua, Dr. Deepthy Menon, Asok, A., Nair, S., and Dr. Manzoor K., “Folate Receptor Targeted, Rare-earth Oxide Nanocrystals for Bi-modal Fluorescence and Magnetic Imaging of Cancer Cells”, Biomaterials, vol. 31, pp. 714-729, 2010.

Publisher : Biomaterials

Year : 2010

Folate conjugated carboxymethyl chitosan-manganese doped zinc sulphide nanoparticles for targeted drug delivery and imaging of cancer cells

Cite this Research Publication : M. Ea Mathew, Mohan, J. Ca, Manzoor, Ka, Nair, S. Va, Tamura, Hb, and Jayakumar, Ra, “Folate conjugated carboxymethyl chitosan-manganese doped zinc sulphide nanoparticles for targeted drug delivery and imaging of cancer cells”, Carbohydrate Polymers, vol. 80, pp. 443-449, 2010.

Publisher : Carbohydrate Polymers

Year : 2009

Studies on Structural and Magnetic Properties of Co-doped Pyramidal ZnO Nanorods Synthesized by Solution Growth Technique

Cite this Research Publication : M. Ka Patra, Manzoor, Kb, Manoth, Ma, Vadera, S. Ra, and Kumar, Na, “Studies on Structural and Magnetic Properties of Co-doped Pyramidal ZnO Nanorods Synthesized by Solution Growth Technique”, Journal of Physics and Chemistry of Solids, vol. 70, pp. 659-664, 2009.

Publisher : Journal of Physics and Chemistry of Solids

Year : 2009

The design of novel nanostructures on titanium by solution chemistry for an improved osteoblast response.

Cite this Research Publication : V. V. Divya Rani, Manzoor, K., Dr. Deepthy Menon, Selvamurugan, N., and Shantikumar V Nair, “The design of novel nanostructures on titanium by solution chemistry for an improved osteoblast response.”, Nanotechnology, vol. 20, p. 195101, 2009.

Publisher : Nanotechnology

Year : 2009

Dendrigraft Polymer-based Synthesis of Silver Nanoparticles Showing Bright Blue Fluorescence

Cite this Research Publication : M. Manoth, Koyakutty, M., Patra, M. K., Pandey, P., Vadera, S. R., and Kumar, N., “Dendrigraft Polymer-based Synthesis of Silver Nanoparticles Showing Bright Blue Fluorescence”, Materials Research Bulletin, vol. 44, pp. 714-717, 2009.

Publisher : Materials Research Bulletin

Year : 2009

Bio-conjugated Luminescent Quantum Dots of Doped ZnS: A Cyto-friendly System for Targeted Cancer Imaging

Cite this Research Publication : K. Manzoor, Johny, S., Thomas, D., Setua, S., Menon, D., and Shantikumar V Nair, “Bio-conjugated Luminescent Quantum Dots of Doped ZnS: A Cyto-friendly System for Targeted Cancer Imaging”, Nanotechnology, vol. 20, 2009.

Publisher : Nanotechnology

Year : 2009

Role of Size Scale of ZnO Nanoparticles and Microparticles on Toxicity Toward Bacteria and Osteoblast Cancer Cells

Cite this Research Publication : Shantikumar V. Nair, Abhilash Sasidharan, Rani, V. V. Divya, Dr. Deepthy Menon, Raina, S., and Manzoor, K., “Role of Size Scale of ZnO Nanoparticles and Microparticles on Toxicity Toward Bacteria and Osteoblast Cancer Cells”, Journal of Materials Science: Materials in Medicine, vol. 20, pp. S235-S241, 2009.

Publisher : Journal of Materials Science: Materials in Medicine

Year : 2008

Optically Transparent Colloidal Suspensions of Single Crystalline ZnO Quantum dots Prepared by Simple Wetchemistry

Cite this Research Publication : M. K. Patra, Manzoor, K., Manoth, M., Choudhry, V. S., Vadera, S. R., and Kumar, N., “Optically Transparent Colloidal Suspensions of Single Crystalline ZnO Quantum dots Prepared by Simple Wetchemistry”, Journal of Optoelectronics and Advanced Materials, vol. 10, pp. 2588-2591, 2008.

Publisher : Journal of Optoelectronics and Advanced Materials

Book Chapter

Year : 2016

Nanomedicines Targeted to Aberrant Cancer Signalling and Epigenetics

Cite this Research Publication : A. Retnakumari, Parwathy Chandran, Ramachandran, R., Malarvizhi, G. L., Nair, S., and Dr. Manzoor K., “Nanomedicines Targeted to Aberrant Cancer Signalling and Epigenetics”, in Handbook of Clinical Nanomedicine Nanoparticles, Imaging, Therapy, and Clinical Applications, vol. 1, Pan Stanford Publications USA, 2016.

Publisher : Handbook of Clinical Nanomedicine Nanoparticles, Imaging, Therapy, and Clinical Applications, Pan Stanford Publications USA,

Patents

Year : 2017, 2020

MRI and CT Contrast-enabled Composite Implants for Image-guided Tissue Regeneration and Therapy (Filed)

Cite this Research Publication : Anusha Ashokan, Dr. Manzoor K., Shantikumar V Nair, M, S., and Harish, V., “MRI and CT Contrast-enabled Composite Implants for Image-guided Tissue Regeneration and Therapy (Filed)”, U.S. Patent PCT/US2017/0207932017.

Publisher : Amrita Vishwa Vidyapeetham,

Year : 2018

Nanoparticle formulations for delivering multiple therapeutic agents

Cite this Research Publication : Dr. Manzoor K., Malarvizhi, G. Loghanatha, and Shantikumar V Nair, “Nanoparticle formulations for delivering multiple therapeutic agents ”, 2017.

Publisher : US Patent 10143700B2

Year : 2017, 2018

Nanoparticle formulations for delivering multiple therapeutic agents

Cite this Research Publication : Dr. Manzoor K., Malarvizhi, G. Loghanatha, and Shantikumar V Nair, “Nanoparticle formulations for delivering multiple therapeutic agents ”, 2017.

Publisher : Nanoparticle Formulations for Delivering Multiple Therapeutic Agents

Year : 2015, 2017

Radio-Wave Responsive Doped Nanoparticles for Image Guided Therapeutics (Filed)

Cite this Research Publication : r. Manzoor K., Anusha Ashokan, Harish, V., and Nair, S., “Radio-wave Responsive Doped Nanoparticles for Image Guided Therapeutics ”, U.S. Patent WO2017096342A1 (Filed)2017.

Publisher : U.S. Patent

Year : 2017

Single Substrate for Combined Raman-Mass Spectroscopic Analysis of Biological and Chemical Samples

Cite this Research Publication : C. Madathil Girish, Dr. Manzoor K., and K, S., “Single Substrate for Combined Raman-Mass Spectroscopic Analysis of Biological and Chemical Samples”, 2017.

Year : 2017

Non-Iodinated Radiolabeled Radiopaque Microbeads with MRI Contrast for Radioembolization (Filed)

Cite this Research Publication : Anusha Ashokan, Dr. Manzoor K., Shantikumar V Nair, and Harish, V., “Non-Iodinated Radiolabeled Radiopaque Microbeads with MRI Contrast for Radioembolization (Filed)”, U.S. Patent PCT/US2017/0334862017.

Publisher : U.S. Patent

Year : 2017, 2020

MRI and CT Contrast-enabled Composite Implants for Image-guided Tissue Regeneration and Therapy (Filed)

Cite this Research Publication : Anusha Ashokan, Dr. Manzoor K., Shantikumar V Nair, M, S., and Harish, V., “MRI and CT Contrast-enabled Composite Implants for Image-guided Tissue Regeneration and Therapy (Filed)”, U.S. Patent PCT/US2017/0207932017.

Publisher : Amrita Vishwa Vidyapeetham,

Year : 2017

MRI and CT Contrast-enabled Composite Implants for Image Guided Tissue Regeneration and Therapy

Cite this Research Publication : Dr. Manzoor K., M, S., A, A., Harish, V., and Nair, S., “MRI and CT Contrast-enabled Composite Implants for Image Guided Tissue Regeneration and Therapy”, U.S. Patent WO2017152127, PCT/US2017/ (filed)2017.

Publisher : U.S. Patent

Year : 2017

Compositions and Methods for Autoimmune Disease Treatment Inventors

Cite this Research Publication : Bernard, C. C. A., Krishnakumar N. Menon, Sadanandan, P., Payne, N. L., and Shantikumar V Nair, “Compositions and Methods for Autoimmune Disease Treatment Inventors”, U.S. Patent Australian Provisional Patent Application no: 2016903294 (Patent Filed)2017.

Publisher : U.S. Patent Australian Provisional Patent Application

Year : 2017

Total Serum Protein Nanoparticles and Compositions Thereof for Therapeutic and Imaging Applications

Cite this Research Publication : Dr. Manzoor K., ,, and Nair, S., “Total Serum Protein Nanoparticles and Compositions Thereof for Therapeutic and Imaging Applications ”, U.S. Patent 2017410146152017.

Publisher : U.S. Patent

Year : 2017

Total Serum Protein Nanoparticle and Composition thereof for Therapeutic and Imaging Applications

Cite this Research Publication : Dr. Manzoor K., Nair, S., and Jyotsna Thayath, “Total Serum Protein Nanoparticle and Composition thereof for Therapeutic and Imaging Applications”, U.S. Patent 2017410146152017.

Publisher : U.S. Patent

Year : 2017, 2018

Nanoparticle formulations for delivering multiple therapeutic agents

Cite this Research Publication : Dr. Manzoor K., Malarvizhi, G. Loghanatha, and Shantikumar V Nair, “Nanoparticle formulations for delivering multiple therapeutic agents ”, 2017.

Publisher : Nanoparticle Formulations for Delivering Multiple Therapeutic Agents

Year : 2017

Targeted nano-photomedicines for photodynamic therapy of cancer

Cite this Research Publication : Dr. Manzoor K., Robinson, D. J., Sterenborg, H. J. C. M., Kascakova, S., and Nair, S., “Targeted nano-photomedicines for photodynamic therapy of cancer”, 2017.

Publisher : Volume European Patent EP 2440247 B1 (2017)

Year : 2016

Non-iodinated Radiopaque Microbeads, Capable of Binding to Radioisotopes for Trans-arterial Embolization and Trans-arterial Radioembolization

Cite this Research Publication : Dr. Manzoor K., Harish, V., Anusha Ashokan, and Nair, S., “Non-iodinated Radiopaque Microbeads, Capable of Binding to Radioisotopes for Trans-arterial Embolization and Trans-arterial Radioembolization”, U.S. Patent PCT No 201641017865 (Filed)2016.

Publisher : Number PCT No 201641017865 (Filed) .

Year : 2016

Core-shell particle formulation for delivering multiple therapeutic

Cite this Research Publication : Shantikumar V Nair, Dr. Manzoor K., and P, A., “Core-shell particle formulation for delivering multiple therapeutic”, 2016.

Publisher : Volume US Patent 9402918.

Year : 2015, 2017

Radio-Wave Responsive Doped Nanoparticles for Image Guided Therapeutics (Filed)

Cite this Research Publication : r. Manzoor K., Anusha Ashokan, Harish, V., and Nair, S., “Radio-wave Responsive Doped Nanoparticles for Image Guided Therapeutics ”, U.S. Patent WO2017096342A1 (Filed)2017.

Publisher : U.S. Patent

Year : 2014

Photo – chemo composition on the basis of microcapsules with a core -shell structure

Cite this Research Publication : K. Manzoor, R. Ranjith, Giridharan, L. M., and Shantikumar, V. N., “Photo - chemo composition on the basis of microcapsules with a core -shell structure”, U.S. Patent PCT/IN2013/0001442014.

Publisher : Amrita Vishwa Vidyapeetham,

Year : 2014

Stannous Doped Micro and Nano Particles for Augmented Radiofrequency Ablation

Cite this Research Publication : V. Harish, Dr. Manzoor K., and Nair, S., “Stannous Doped Micro and Nano Particles for Augmented Radiofrequency Ablation”, U.S. Patent PCT/US2014/011153 (Filed)2014.

Publisher : Amrita Vishwa Vidyapeetham

Year : 2014

A Method for Making Single-Source Precursor for Semiconductor Nanocrystals

Cite this Research Publication : Dr. Manzoor K., Verma, A., Vedera, S. Raj, Kutty, T. Raman Nara, and Narendra Kumar, “A Method for Making Single-Source Precursor for Semiconductor Nanocrystals”, 2014.

Year : 2014

A core-shell nanostructure on the basis of proteins with corresponding therapeutic agents

Cite this Research Publication : Dr. Manzoor K., Retnakumari, A., and Shantikumar V Nair, “A core-shell nanostructure on the basis of proteins with corresponding therapeutic agents”, U.S. Patent PCT/IN2013/0001412014.

Publisher : U.S. Patent PCT/IN2013/0001412014

Year : 2014

Nano surface modified metallic titanium implants for orthopaedic or dental applications and method of manufacturing thereof

Cite this Research Publication : Dr. Deepthy Menon, Shantikumar V. Nair, Dr. Manzoor K., Rani, V. V. Divya, and Lakshmanan, V. Kumar, “Nano surface modified metallic titanium implants for orthopaedic or dental applications and method of manufacturing thereof”, U.S. Patent PCT/IN2012/0007862014.

Publisher : Amrtia Vishwa Vidyapeetham.

Year : 2013

The art, method,manner process and system of fibrous bio-degradable polymeric wafers for the local delivery of therapeutic agents in combinations

Cite this Research Publication : R. Ramachandran, Dr. Manzoor K., and Shantikumar V Nair, “The art, method,manner process and system of fibrous bio-degradable polymeric wafers for the local delivery of therapeutic agents in combinations”, U.S. Patent PCT/IN2013/0001102013.

Publisher : Amrita Vishwa Vidyapeetham

Year : 2013

Polymer – polymer or polymer – protein core – shell nano medicine loaded with multiple drug molecules

Cite this Research Publication : Dr. Manzoor K., PARWATHY, C., Archana, P. R., and Shantikumar V Nair, “Polymer - polymer or polymer - protein core - shell nano medicine loaded with multiple drug molecules”, U.S. Patent PCT/IN2013/0001082013.

Publisher : U.S. Patent PCT/IN2013/0001082013

Year : 2012

Targeted nano-photomedicines for photodynamic therapy of cancer

Cite this Research Publication : M. Koyakutty, Robinson, D. J., Sterenborg, H. J. C. M., Kascakova, S., and Shantikumar V Nair, “Targeted nano-photomedicines for photodynamic therapy of cancer”, U.S. Patent EP200907881932012.


Publisher : Amrita Vishwa Vidyapeetham, Erasmus University Medical Center

Year : 2012

Polymer-Polymer and Polymer-Protein Core-shell Nanomedicine loaded with Multiple Drug Molecule

Cite this Research Publication : Dr. Manzoor K., Parvathy Chandran, and R, A. P., “Polymer-Polymer and Polymer-Protein Core-shell Nanomedicine loaded with Multiple Drug Molecule”, U.S. Patent Application # 644/CHE/2012 A, PCT/IN2013/0001082012.

Publisher : U.S. Patent Application

Year : 2012

THE ART, METHOD, MANNER, PROCESS AND SYSTEM OF CORE-SHELL PHOTO-CHEMO NANOMEDICINE AND METHOD OF TREATING THE CANCER WITH THE SAME

Cite this Research Publication : Dr. Manzoor K., Ramachandran, R., M, G. L., and Nair, S., “THE ART, METHOD, MANNER, PROCESS AND SYSTEM OF CORE-SHELL PHOTO-CHEMO NANOMEDICINE AND METHOD OF TREATING THE CANCER WITH THE SAME”, U.S. Patent 24/CHE/20122012.

Publisher : U.S. Patent

Year : 2012

THE ART, METHOD, MANNER, PROCESS AND SYSTEM OF MULTIFUNCTIONAL NANOMEDICINE FOR MOLECULAR IMAGING AND SCINTILLATION THERAPY

Cite this Research Publication : Dr. Manzoor K., Shantikumar V Nair, Dr. Deepthy Menon, and Asok, A., “THE ART, METHOD, MANNER, PROCESS AND SYSTEM OF MULTIFUNCTIONAL NANOMEDICINE FOR MOLECULAR IMAGING AND SCINTILLATION THERAPY”, U.S. Patent 26/CHE/20122012.

Publisher : U.S. Patent

Year : 2012

The Art, Method, Manner, Process and System of protein-protein nanomedicine comprising more than one therapeutic molecule

Cite this Research Publication : Dr. Manzoor K., Retnakumari, A., and Nair, S., “The Art, Method, Manner, Process and System of protein-protein nanomedicine comprising more than one therapeutic molecule”, U.S. Patent 2550/CHE/2012, US 14/585,0132012.

Publisher : U.S. Patent

Year : 2011

Nanosurface Modified Metallic Titanium Implants for Orthopedic or Dental Applications

Cite this Research Publication : D. Menon, Shantikumar V. Nair, Dr. Manzoor K., V, D., and Lakshmanan, V. Kumar, “Nanosurface Modified Metallic Titanium Implants for Orthopedic or Dental Applications”, U.S. Patent #1644/CHE/20112011.

Publisher : U.S. Patent

Year : 2011

The Art, Method, Maner, Process and System of Protien-Sorafenib Nanomedicine

Cite this Research Publication : Dr. Manzoor K., Retnakumari, A., and Shantikumar V Nair, “The Art, Method, Maner, Process and System of Protien-Sorafenib Nanomedicine”, U.S. Patent 3455/CHE/20112011.

Publisher : Dr. Manzoor K., Retnakumari, A., Shantikumar V Nair

Year : 2010

The Art, Manner, Method and Process of Preparation of Fibrinogen Nanoparticles by a Simple Two-Step Co-acervation Method for Drug Delivery Applications

Cite this Research Publication : “The Art, Manner, Method and Process of Preparation of Fibrinogen Nanoparticles by a Simple Two-Step Co-acervation Method for Drug Delivery Applications ”, 2018.

Publisher : Volume Indian Patent

Year : 2010

THE ART, MANNER, METHOD AND PROCESS OF PREPARATION OF CHITOSAN SPONGE CONTAINING THE HERB COLEUS PLECTRANTBUS AS A WOUND DRESSING

Cite this Research Publication : Dr. Jayakumar Rangasamy, Manzoor, K., Shantikumar V Nair, Lakshmanan, V. K., Kumar, P. T. Sudheesh, and Abhilash, S., “THE ART, MANNER, METHOD AND PROCESS OF PREPARATION OF CHITOSAN SPONGE CONTAINING THE HERB COLEUS PLECTRANTBUS AS A WOUND DRESSING”, U.S. Patent 3012/CHE/20102010.

Publisher : U.S. Patent

Year : 2010

The Art, Method, Manner, Process and System of Chitosan hydrogel / Nano Zinc Oxide Membranes for Wound Dressing Applications

Cite this Research Publication : Dr. Jayakumar Rangasamy, Dr. Manzoor K., Shantikumar V Nair, Lakshmanan, V. K., Kumar, P. T. Sudheesh, and Abhilash, S., “The Art, Method, Manner, Process and System of Chitosan hydrogel / Nano Zinc Oxide Membranes for Wound Dressing Applications”, U.S. Patent 1025/CHE/20102010.

Publisher : U.S. Patent

Year : 2009

Multifunctional Nanobiomaterial for Molecular Imaging and Drug Delivery

Cite this Research Publication : Dr. Manzoor K., Anusha Ashokan, Menon, D., and Shantikumar V. Nair, “Multifunctional Nanobiomaterial for Molecular Imaging and Drug Delivery”, U.S. Patent # 2633/CHE/20092009.

Publisher : U.S. Patent

Book

Year : 2012

Biomedical Applications of Graphene: Opportunities and Challenges

Cite this Research Publication : Dr. Manzoor K., Abhilash Sasidharan, and Nair, S., Biomedical Applications of Graphene: Opportunities and Challenges. Wiley-VCH, 2012, pp. 373-408.

Publisher : Wiley-VCH

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