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Dr. Prashant S.

Assistant Professor, Pharmaceutical Chemistry & Analysis, School of Pharmacy, Kochi

Qualification: Ph.D
prashants@pharmacy.aims.amrita.edu
Research Interest: Autoimmunity, Engineering of Multifunctional Nanomaterials for Drug Delivery

Bio

Dr. Prashant is currently working as an Assistant Professor in the Department of Pharmaceutical Chemistry, Amrita School of Pharmacy. He joined as a Lecturer at the School of Pharmacy in 2017. He completed his Ph. D. in the Faculty of Pharmacy from the Centre for Nanosciences and Molecular Medicine, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham in 2022. He did his post-graduation from the National Institute of Pharmaceutical Education and Research (NIPER), Mohali in 2010-2012. His Bachelor’s degree in Pharmacy was from the Govt. Medical College, Thiruvananthapuram.

His Master’s thesis research work entitled ‘Exploration of Non-Shikimic Acid based synthetic routes for the Neuraminidase Inhibitor – Oseltamivir’ was under the guidance of Dr. Asit K Chakraborti (Head, Department of Medicinal Chemistry, NIPER). He had worked for 1 year in Ravi Institute of Medical Sciences, Kerala (2013) before he joined as Senior Research Fellow in 2014 at Amrita Centre for Nanosciences in an Indo Australian Biotechnology Fund, a collaborative project with Monash University, Australia.

His doctorate work entitled “Nanoengineeed autoantigens for the treatment of autoimmune disease Multiple Sclerosis” was under the guidance of Professor Dr. Manzoor K and Dr. Krishnakumar Menon, Professors at Amrita Centre for Nanosciences and Molecular Medicine. He was a visiting Ph.D scholar at Prof. Dr. Claude Bernard Lab of Australian Regenerative Medicine Institute, Monash University, Australia. In the Ph.D work, he developed splenic-macrophage-specific, biodegradable nanoparticles for the antigenic peptide delivery for inducing tolerance in the autoimmune models. This work was filed for a US patent and was published in the Nanomedicine: NBM and European Journal of Immunology journals.

Publications

Journal Article

Year : 2022

Bacopa monnieri for disorders affecting brain: Current perspectives

Cite this Research Publication : Adithya V, S Sathianarayanan, Anju Elizabath, Prashant Sadanandan, KV Athira, Baskar V. Bacopa monnieri for disorders affecting brain: Current perspectives. Current topics in medicinal chemistry, 2022. doi: 10.2174/1568026622666220119111538

Publisher : Current topics in medicinal chemistry

Year : 2022

Exploiting the preferential phagocytic uptake of nanoparticle-antigen conjugates for the effective treatment of autoimmunity

Cite this Research Publication : Prashant Sadanandan, Natalie P, Guizhi S, Anusha A, Siddaramana G, Arsha L, Satheesh K, Sreeranjini P, S V Nair, K N Menon, Claude Bernard, Manzoor K. Exploiting the preferential phagocytic uptake of nanoparticle-antigen conjugates for the effective treatment of autoimmunity. Nanomedicine: Nanotechnology, Biology and Medicine, 2022, 40, 102481. doi: 10.1016/j.nano.2021.102481

Publisher : Nanomedicine: Nanotechnology, Biology and Medicine

Year : 2021

Repurposing Vorinostat for the Treatment of Disorders Affecting Brain

Cite this Research Publication : Athira, K.V., Sadanandan, P., Chakravarty, S., "Repurposing Vorinostat for the Treatment of Disorders Affecting Brain," NeuroMolecular Medicine, 2021, 23(4), pp. 449-465, doi: 10.1007/s12017-021-08660-4. Epub 2021 May 4.

Publisher : NeuroMolecular Medicine

Year : 2020

Evaluation of Kaempferol as AKT Dependent mTOR Regulator via Targeting FKBP-12 in Hepatocellular Carcinoma: an In silico Approach

Cite this Research Publication : Siniprasad P, Nair B, Balasubramaniam V, Sadanandan, Prashant, Namboori P K, Nath L R. Evaluation of Kaempferol as AKT Dependent mTOR Regulator via Targeting FKBP-12 in Hepatocellular Carcinoma: An In silico Approach. Letters in Drug Design & Discovery, 2020, 17 (11), 1401-1408. doi: 10.2174/1570180817999200623115703

Publisher : Letters in Drug Design & Discovery

Year : 2016

Nanoengineered Myelin Oligodendrocyte Glycoprotein Peptides Suppressed Experimental Autoimmune Encephalomyelitis: Implications In Multiple Sclerosis Therapy

Cite this Research Publication : Prashant Sadanandan, N Payne, G Sun, A Ashokan, Wilbin X, S G Gowd, S V Nair, K N Menon, Claude Bernard, Manzoor K. Nanoengineered myelin oligodendrocyte glycoprotein peptides suppressed experimental autoimmune encephalomyelitis: Implications in Multiple Sclerosis therapy. European Journal of Immunology, 2016, 46 (1), 316-317. doi: 10.1002/eji.201670200

Publisher : European Journal of Immunology

Book Chapter

Year : 2022

Preparation of Biological Samples for SEM: Techniques and Procedures

Cite this Research Publication : Sreejith M, Prashant Sadanandan, Sonu Benny, Aneesh T P. Preparation of Biological Samples for SEM: Techniques and Procedures. Book Title: Microscopic Techniques for Non-Expert. Publisher: Springer Nature. ISBN: 978-3-030-99541-6.

Publisher : Springer Nature

Year : 2022

Cardiovascular disease comorbidity in major depressive disorder

Cite this Research Publication : Anju J, Anju Elizabath, Prashant Sadanandan, Athira K V. Cardiovascular disease comorbidity in major depressive disorder. Book Title: Recent Advancements and Research in Biological Sciences. Publisher: Thanuj international publishers. ISBN: 978-81-952529-1-6.

Publisher : Thanuj international publishers

Year : 2005

Cyclodextrin in drug delivery

Cite this Research Publication : Anju J, Sreeja V, Prashant Sadanandan, Athira K V. Cyclodextrin in drug delivery. Book Title: Natural Biopolymers in Drug Delivery and Tissue Engineering. Publisher: Elsevier (Under Revision).

Publisher : Elsevier

Patents

Year : 2017

Compositions and Methods for Autoimmune Disease Treatment

Cite this Research Publication : Compositions and methods for autoimmune disease treatment. Manzoor Koyakutty, Krishnakumar N Menon, Claude C. A. Bernard, Prashant Sadanandan, Natalie L Payne, Shantikumar V Nair. PCT Application No. PCT/US17/47778. United States Patent Application Publication no: US20200246441A1

Publisher : United States Patent

Awards and Fellowships
  • First prize in Oral presentation in the International Conference – Pharmainnovations 2022 organized by Chemist College of Pharmaceutical Sciences and Research, August 2022
  • First prize in Oral presentation in the International webinar on Biomaterials organized by Amrita Vishwa Vidyapeetham and Society for Biomaterials and Artificial Organs India (SBAOI), March 2022
  • Young Researcher Award-2021 by Society of Young Biomedical Scientists, in the National Biomedical Research Competition (NBRCOM-2021), India.
  • CSIR Govt. of India, Senior Research Fellowship Award, Feb 2017
  • Bill & Melinda Gates Foundation Grant for Oral presentation at International Congress of Immunology (ICI) 2016, Melbourne, Australia (2000 USD).
  • Best Paper Award, Indian Chemical Society, 50th Annual Convention of Chemists, Panjab University, Dec 2013.
  • NIPER JEE Fellowship, 2010-2012
  • Qualified NIPER JEE Exam conducted by Ministry of Chemicals and Fertilizers, Govt. of India, 2010 (Top 10%).
  • Qualified Graduate Pharmacy Aptitude Test (GPAT) conducted by MS University Baroda, 2010 (Top 10 %).
  • ACS award for the Best Oral Presentation in the International conference on Biomaterials, Regenerative Medicine and Devices (BIO-Remedi), organized by IIT-Guwahati, SBAOI, and STERMI on December 2022
  • Best Oral Presentation Award in the Indo-US Seminar- Recent Biochemical Approaches in Therapeutics, organized by University of Kerala and University of Wisconsin, USA, on Feb 2023
  • Best Oral Presentation Award by IBRO (International Brain Research Organization) in the International Conference on Nanopharmaceuticals and Neurological Disorders (ICNAND 2023) organized by IGNTU, India, on Feb 2023
  • First Prize in Oral Presentation Awards at the 1st Kerala Pharmaceutical Congress, organized by Kerala Pharmaceutical Graduate Association (KPGA), on Feb 2023
Invited Talks
  • Nanotechnology based approaches in the treatment of Autoimmunity (January 28, 2023) organized by NITTE, Mangalore.
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