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Dr.Rejithamol R.

Assistant Professor (Sr. Grd.), Department of Chemistry, School of Physical Science, Amritapuri

Qualification: MSc, Ph.D
rejithamolr@am.amrita.edu
Ph: 9746753452
Research Interest: Biological Applications, Organic Synthesis

Bio Publications Awards Research Ongoing Projects Collaborations Student Guidance Workshop Conferences Attended
Bio

Dr. Rejithamol R currently serves as Assistant Professor (Sr. Gr.) at the Department of Chemistry, Amrita School of Physical Sciences, Amrita Vishwa Vidyapeetham, Kerala, India. Dr. Rejitha joined the Department of Chemistry at Amrita in 2013 and she obtained her Ph.D. in analytical chemistry from, Amrita Vishwa Vidyapeetham in 2021. Her research interest includes the fabrication of electrochemical sensors for biomolecules, food additives, environmental pollutants, and phytochemical analysis of plant extracts. She has published several research articles in reputed national and international journals in electrochemical sensors and phytochemistry.

Education

  • 2015 – 2020 : Ph.D*, Analytical Chemistry
    Amrita Vishwa Vidyapeetham
  • 2007 – 2009 : M. Sc. Chemistry
    MG University, First Class
  • 2004 – 2007 : B.Sc. Chemistry
    MG University, First Class Distinction

*Thesis entitled “Electro polymer based Voltammetric sensor for the analysis of biomolecules”

Publications

Journal Article

Year : 2023

Biopolymer supported electroanalytical methods for the determination of biomolecules and food additives – a comprehensive perspective

Cite this Research Publication : R. Rejithamol, Devu Chandran, Sreelekshmi P J, Devika V, Agraja P S, Maheswari K and Vedhanarayanan Balaraman, Biopolymer Supported Electroanalytical Methods for the Determination of Biomolecules and Food Additives – A Comprehensive Perspective, Analytical Methods, 2023.

Year : 2023

In situ polymerization of meta nitro benzoic acid on graphite electrode as a mediator for the electrochemical oxidation of resorcinol

Cite this Research Publication : In-situ polymerization of meta nitro benzoic acid on graphite electrode as a mediator for the electrochemical oxidation of resorcinol. C Devu, SJ Kaveri, P Dhiya, MS Aiswarya, K C Seethalekshmi and R Rejithamol, Journal of Applied Electrochemistry, 2023.

Publisher : Springer

Year : 2022

Fabrication of Pyromellitic Acid Polymer Modified Electrochemical Sensor for the Determination of Tryptophan

Cite this Research Publication : R. Rejithamol, S. Adwaitha, G. Darsana, M.v. Sreenidhi, R. Rajeswary, M. Abhirami And R. Reshma, Fabrication of Pyromellitic Acid Polymer Modified Electrochemical Sensor for the Determination of Tryptophan, Asian Journal of Chemistry; Vol. 34, No. 6 (2022), 1526-1530.

Year : 2022

Carbon Paste Electrochemical Sensors for the Detection of Neurotransmitters

Cite this Research Publication : R. Rejithamol, S. Beena, Carbon Paste Electrochemical Sensors for the Detection of Neurotransmitters, Front. Sens. 3:901628 (2022)

Year : 2021

Electrochemical response of poly-2,4-dinitrophenyl hydrazine and poly phenyl hydrazine-based pencil graphite electrodes for thrombotonin

Cite this Research Publication : R. Rejithamol and Dr. Beena S., “Electrochemical response of poly-2,4-dinitrophenyl hydrazine and poly phenyl hydrazine-based pencil graphite electrodes for thrombotonin”, MRS Advances, IF-0.79, Q3, 2021.

Publisher : MRS Advances, IF-0.79, Q3, 2021.

Year : 2021

Disposable pencil graphite electrode decorated with a thin film of electro-polymerized 2, 3, 4, 6, 7, 8, 9, 10-octahydropyrimido [1, 2-a] azepine for simultaneous voltammetric analysis of dopamine, serotonin and tryptophan

Cite this Research Publication : R. Rejithamol, Krishnan, R. G., and Dr. Beena S., “Disposable pencil graphite electrode decorated with a thin film of electro-polymerized 2, 3, 4, 6, 7, 8, 9, 10-octahydropyrimido [1, 2-a] azepine for simultaneous voltammetric analysis of dopamine, serotonin and tryptophan”, Materials Chemistry and Physics, vol. 258, p. 123857, 2021

Publisher : Materials Chemistry and Physics

Year : 2020

Electrochemical Quantification of L-tryptophan Via Molecular Imprinted Pyromellitic Acid Polymer-Based Indium Tin Oxide Electrode

Cite this Research Publication : R. Rejithamol, G. K. Rajasree, and Dr. Beena S., “Electrochemical Quantification of L-tryptophan Via Molecular Imprinted Pyromellitic Acid Polymer-Based Indium Tin Oxide Electrode”, Journal of The Electrochemical Society, vol. 167, p. 117507, 2020.

Publisher : Journal of The Electrochemical Society, The Electrochemical Society, Volume 167, Number 11, p.117507 (2020)

Year : 2020

Electrochemical quantification of pyridoxine (VB6) in human blood from other water-soluble vitamins

Cite this Research Publication : R. Rejithamol and Dr. Beena S., “Electrochemical quantification of pyridoxine (VB6) in human blood from other water-soluble vitamins”, Chemical Papers, vol. 74, no. 6, pp. 2011 - 2020, 2020

Publisher : Chemical Papers

Year : 2020

Non-enzymatic electrochemical sensor for the simultaneous determination of adenosine, adenine and uric acid in whole blood and urine

Cite this Research Publication : R. G. Krishnan, Rejithamol, R., and Dr. Beena S., “Non-enzymatic electrochemical sensor for the simultaneous determination of adenosine, adenine and uric acid in whole blood and urine”, Microchemical Journal, vol. 155, p. 104745, 2020

Publisher : Microchemical Journal

Year : 2020

One pot synthesis of amino-ethanethiol derivatives of aromatic aldehydes by the catalytic action of DBU

Cite this Research Publication : R. Rejithamol, Dr. Beena S., Krishnan, M., Dharan, M. T., and Anusree, L., “One pot synthesis of amino-ethanethiol derivatives of aromatic aldehydes by the catalytic action of DBU”, IOP Conference Series: Materials Science and Engineering, vol. 872, p. 012121, 2020

Publisher : IOP Publishing

Year : 2019

Synthesis and characterization of phenylacrylonitrile derivatives of aromatic aldehydes in presence of DBU

Cite this Research Publication : R. Rejithamol, Dr. Beena S., Sajitha, C. S., Dileep, N. K. Malavika, Drisya, A., and Keerthi, P. R., “Synthesis and characterization of phenylacrylonitrile derivatives of aromatic aldehydes in presence of DBU”, IOP Conference Series: Materials Science and Engineering, vol. 561, p. 012017, 2019

Publisher : IOP Conference Series: Materials Science and Engineering

Year : 2019

A novel disposable pencil graphite electrode for the voltammetric determination of cysteamine

Cite this Research Publication : R. R, R, K. P., and Dr. Beena S., “A novel disposable pencil graphite electrode for the voltammetric determination of cysteamine”, Materials Today: Proceedings, vol. 18, pp. 5081 - 5086, 2019

Publisher : Materials Today: Proceedings

Year : 2018

Synthesis, Characterization and Photophysical Properties of Benzylidene-Fluorene Derivatives

Cite this Research Publication : Rejithamol, R., Beena, S., Nair, A.B. and Santhy, A., 2018. Synthesis, Characterization and Photophysical Properties of Benzylidene-Fluorene Derivatives. Materials Today: Proceedings, 5(9), pp.17694-17698.

Publisher : International Conference on Materials Processing and Characterization

Year : 2018

Phosphorus species in core sediment and its relation with sediment characteristics of paravur estuary, south west coast of India

Cite this Research Publication : A Santhy and Rejithamol, R., “Phosphorus species in core sediment and its relation with sediment characteristics of paravur estuary, south west coast of India”, 2018Rasayan Journal of chemistry, vol. 11, pp. 1067 - 1073 , 2018.

Publisher : 2018Rasayan Journal of chemistry

Year : 2018

PVC membrane Sensor Immobilized with Clopidogrel-Tetraiodo Bismuthate for the Potentiometric Determination of Clopidogrel from Pharmaceutical Formulations

Cite this Research Publication : A. Santhy, Dr. Beena S., P. Sankar, U., Vidya, R., and Rejithamol, R., “PVC membrane Sensor Immobilized with Clopidogrel-Tetraiodo Bismuthate for the Potentiometric Determination of Clopidogrel from Pharmaceutical Formulations”, Materials Today: Proceedings, vol. 5, pp. 17812 - 17819, 2018

Publisher : Materials Today: Proceedings,

Year : 2017

A facile synthesis of α-hydrazino ketones from 1,3-dicarbonyl compounds using 1,8-diazobicyclo[5.4.0]undec-7-ene (DBU) as organic catalyst

Cite this Research Publication : R. Rejithamol, K. Aparna, S. Swetha, A. Gayathri, and S. Jisha, “A facile synthesis of α-hydrazino ketones from 1,3-dicarbonyl compounds using 1,8-diazobicyclo[5.4.0]undec-7-ene (DBU) as organic catalyst”, Asian Journal of Chemistry, vol. 29, pp. 1963-1965, 2017.

Publisher : Asian Journal of Chemistry

Year : 2012

A facile four component protocol for the synthesis of dihydropyridine derivatives

Cite this Research Publication : Vijay Nair, Anu Jose, K. C. Seetha Lakshmi, Rejithamol, R., and Eringathodi Suresh, “A facile four component protocol for the synthesis of dihydropyridine derivatives”, Org. Biomol. Chem., vol. 10, pp. 7747-7752, 2012.

Publisher : The Royal Society of Chemistry

Year : 2011

A novel NHC-catalyzed transformation of 2H-chromene-3-carboxaldehydes to 3-methyl-2H-chromen-2-ones

Cite this Research Publication : Vijay Nair, C. R. Sinu, Rejithamol, R., K. C. Seetha Lakshmi, and Eringathodi Suresh, “A novel NHC-catalyzed transformation of 2H-chromene-3-carboxaldehydes to 3-methyl-2H-chromen-2-ones”, Org. Biomol. Chem., vol. 9, pp. 5511-5514, 2011.

Publisher : The Royal Society of Chemistry

Year : 2011

A facile Multicomponent Reaction Involving Isoquinoline, Dimethylallene Dicarboxylate and 2-oxo-1H-Indole-3-Ylidenes

Cite this Research Publication : R. Rejithamol, Beneesh Pattoorpad Babu, and Vijay Nair, “A facile Multicomponent Reaction Involving Isoquinoline, Dimethylallene Dicarboxylate and 2-oxo-1H-Indole-3-Ylidenes”, Synthesis, 2011.

Publisher : Synthesis

Conference Paper

Year : 2017

Clopidogrel-tetralodo mercurate ion association immobilized PVC membrane sensor for the determination of clopidogrel in pharmaceutical formulations

Cite this Research Publication : Dr. Beena S., A Santhy, R Vidya, P Uma Sankar, and Rejithamol, R., “Clopidogrel-tetralodo mercurate ion association immobilized PVC membrane sensor for the determination of clopidogrel in pharmaceutical formulations”, in 2017 International Conference on Technological Advancements in Power and Energy (TAP Energy), Kollam, India, 2017.

Publisher : 2017 International Conference on Technological Advancements in Power and Energy (TAP Energy)

Year : 2014

DBU CATALYZED α- AMINATION OF 1, 3-DICARBONYL COMPOUNDS

Cite this Research Publication : Surya Bhaskar, Reshma G R, and Rejithamol, R., “DBU CATALYZED α- AMINATION OF 1, 3-DICARBONYL COMPOUNDS”, in National symposium on transcending frontiers in organic chemistry, 2014.

Publisher : National symposium on transcending frontiers in organic chemistry

Year : 2014

A Novel Multicomponent Reaction Involving Isoquinoline-Allenoate Zwitterion for the Synthesis of Spiro[indoline-3,2’-pyrido[2,1- a]isoquinoline]-3’-carboxylates

Cite this Research Publication : R. Rejithamol and Dr. G Vijay Nair, “A Novel Multicomponent Reaction Involving Isoquinoline-Allenoate Zwitterion for the Synthesis of Spiro[indoline-3,2’-pyrido[2,1- a]isoquinoline]-3’-carboxylates”, in 16th CRSI National symposium in chemistry, 2014.

Publisher : 16th CRSI National symposium in chemistry

Conference Proceedings

Year : 2014

DBU CATALYZED α- AMINATION OF 1,3-DICARBONYL COMPOUNDS(Poster)

Cite this Research Publication : Surya Bhaskar, Reshma G R, and Rejithamol, R., “DBU CATALYZED α- AMINATION OF 1,3-DICARBONYL COMPOUNDS(Poster)”, National Symposium on Transcending Frontiers In Organic Chemistry. NIIST Trivandrum , 2014.

Publisher : National Symposium on Transcending Frontiers In Organic Chemistry

Awards
  1. Graduate Aptitude Test in Engineering (GATE), 2010.
  2. CSIR JRF (2011)
  3. Certificate of Appreciation in 2020 from Amrita Vishwa Vidyapeetham for all-round best performance in the academic year 2019-2020 (given on an annual basis to appreciate significant contributions in that year)
Research

Ongoing Research

  • Biopolymer Based Electrochemical Sensors for Synthetic food Colorants/Environmental pollutants/biomolecules: The development of fast, rapid, and cost-effective methods for the determination of biologically important molecules has attracted considerable attention in many areas such as clinical, diagnostic, biochemical and food industries. Nowadays, the main problem faced by Human health is food safety and environmental issues. Food poisoning adversely affects the economy, trade, and industry of affected countries. Early and accurate detection of food safety is critical to preventing, controlling, and mitigating the effects of potential outbreaks. Evidence of many test insufficiencies and carcinogenicity, genotoxicity, and hypersensitivity is consistent with the fact that color does not improve food safety or nutritional value. The increase in the number of potentially harmful pollutants in the environment, especially food security, has created a need for the development of efficient analytical methods for their detection. Electrochemical sensors are emerging as suitable analytical tools as they provide a low-cost and sensitive tool based on portable devices capable of rapidly detecting a range of analytes with high sensitivity and specificity. Electrochemical methods play an important role in the quality control of food processing, improving the quality and safety of products. Because of the more advantageous nature of the electrochemical method, we would like to proceed using it. This method is green, fast analysis, less expensive, increasingly precise, selective, specific, and highly sensitive. Our research focuses on the development of analytical methods and techniques to analyze food samples, medicines, quantification of biomolecules, and detection of various organic and inorganic environmental pollutants.
  • Phytochemical Analysis of Plant Extracts: Natural products have great demand in different industries such as food, pharmaceutical, and cosmetics so the research continues into their potential for new applications. For thousands of years, nature has served as a source of medicine, and an amazing variety of drugs have been separated from it. Examples include alkaloids, glycosides, terpenoids, phenols, tannins, flavonoids and saponins. Additionally, there is increased interest in plant chemistry to find more potent biotherapeutic compounds.  Several studies have already proved that both the flower and leaf possess analgesic, antioxidant, and anti-fungal properties. There are studies that report that the herb possesses anti-cancer properties. The mission is to research the properties of various plant extracts of medicinal importance and demonstrate their pharmacological effects.
  • Fabrication of Enzymatic and Non-Enzymatic Biosensors: Currently our group was engaged in the fabrication of cholesterol biosensors by the conventional way of modifying the electrodes and to develop both enzymatic and non-enzymatic cholesterol biosensors. This fabricated cholesterol biosensor provides a new platform for routine analysis of cholesterol in human blood serum samples
  • Multicomponent reactions for the synthesis of small organic molecules : Carbon-carbon and carbon-heteroatom bond-forming reactions are central to organic synthesis. Different types of reactions such as polar, pericyclic, and radical reactions have been employed by organic chemists for the construction of carbon-carbon and carbon-heteroatom bonds. Among various intermediates involved in polar reactions, a class of potentially useful dipolar species, viz., zwitterions resulting from the addition of nucleophiles to activated π- systems have been of interest to our research group.

Professional Training and Research Experience

  1. Project work as a part of M.Sc. Programme in Chemistry
    Supervisor : Dr. Vijay Nair
    Institute : NIIST (former RRL) Trivandrum, Kerala
    Duration : Five months (2009January – May)
    Thesis Title : Synthesis of oxindole derivatives by the reaction of dimethoxycarbene – DMAD zwitterions with isatins.
    Achieved the basic training in setting up reactions and operating equipment’s.
  2. Research work as a part of Ph.D.programme
    Supervisor : Dr. Beena S
    Institute : Amrita Vishwa Vidyapeetham, Kerala
    Duration : Five years (March 2015 – December 2020)
    Thesis Title : Electro polymer based Voltammetric sensor for the analysis of biomolecules
    Achieved rigorous training in various aspects of analytical chemistry and time-bound research executions.
Ongoing Projects
  • Extraction, identification, and determination of antioxidants activity from the methanolic extract of syzgium cumini seed(Jamun)
  • Extraction, identification, and determination of antioxidants activity from the methanolic extract of Clerodendrum infortunatum Linn leaves (Peuvalam)
  • Extraction, identification, and determination of antioxidants activity from the methanolic extract of CATHARANTHUS ROSEUS leaves
Collaborations
  • Dr. Vedhanarayanan Balaraman, JSPS fellow, Chiba University, Japan
  • Prochip Technology, Kozhikkode (Portable device fabrication for the analysis of food colorants), Kerala, India
  • Dr. Nimisha K, Drug Standardization Unit, Gov. Ayurveda College, Thiruvananthapuram, Kerala, India
  • Dr. Vinayakan R, Assistant Professor, Dept. of Chemistry NSS Hindu college Changanassery, Kerala, India
Student Guidance
  • Devu Chandran- Biopolymer-based electrochemical sensor for synthetic food colorants
  • Devika V- Design and Synthesis of tryptophan-based peptides for studying their bioactivity and electrochemical activity
  • Sreelekshmi P J- Design and Synthesis of dendrimer-coupled bioactive peptides for medicinal applications and their electrochemical study
Workshop

Organized, a two-day hands-on workshop titled electro analytical mastery in collaboration with the Indian Chemical Society (Tamilnadu Branch) as a part of the national-level multi-fest of the Amrita Vishwa Vidyapeetham, Amritapuri campus, Vidyut 2023 on May 7-8, 2023

Conferences Attended
  1. R Rejithamol, Kaveri S J, Dhiya Pradeep, Aiswarya M S, Anjali S and Sneha S, Extraction, Identification, and Phytochemical Analysis of the Leaves of the Methanolic Extract of Clerodendrum Infortunatum Linn, AIP proceedings, 2023.
  2. A Simple And Effective Differential Pulse Voltammetric Method For The Determination Of Resorcinol, Rejithamol R, Devu Chandran, Sreelekhshmi P J and Devika V; held at MATCON International Conference on Materials at CUSAT on January 12-14, 2023.
  3. R. Rejithamol, S. Adwaitha, G. Darsana, Lincy Rajan, Sai Keerthana, Parvathi A, and Lekshmi Priya Ramachandran, A Mini-Review on Carbon Nanomaterials, Electro Polymers, and Metal Oxides Based Electrochemical Sensors for Cysteamine, AIP conference proceeding, 2022.
  4. R. Rejithamol, S. Beena,  K. Midhina,  T. D. Megha, L. Anusree, One pot synthesis of amino-ethanethiol derivatives of aromatic aldehydes by the catalytic action of DBU, IOP Conference Series: Materials Science and Engineering 872 (2020) 012121
  5. R. Rejithamol, S. Beena,  S. Sajitha,  C. S. Drisya, P. R. Keerthi,  Synthesis and characterization of phenyl acrylonitrile derivatives of aromatic aldehydes in presence of DBU, IOP Conference Series: Materials Science and Engineering 561 (2019) 012017
  6. R. Rejithamol, P. R. Keerthy, S. Beena, A novel disposable pencil graphite electrode for the voltammetric determination of cysteamine, Materials Today Proceedings 18 (2019) 5081-5086
  7. R. Rejithamol, S. Beena,  B. N Asha,  Synthesis, characterization and photophysical properties of benzylidene-fluorene derivatives, Materials Today: Proceedings 5 (2018) 17694–17698
  8. S. Beena, A Santhy, R. S. Vidya, R. Rejithamol, Clopidogrel-tetralodo mercurate ion association immobilized PVC membrane sensor for the determination of clopidogrel in pharmaceutical formulations, TAP Energy (2018) 1–5
  9. A. Santhy, S. Beena, P. Uma Sankar, R. Vidya, R. Rejithamol, PVC membrane Sensor Immobilized with Clopidogrel-Tetraiodo Bismuthate for the Potentiometric Determination of Clopidogrel from Pharmaceutical Formulations, Materials Today: Proceedings 5 (2018) 17812-17819
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