Qualification: 
M. Pharm., B. Pham.

Sreesha N. Nair joined as Lecturer in the department of Pharmacognosy, Amrita School of Pharmacy in September 2015. She has completed M. Pharm. and B. Pharm. from University College of Pharmacy , Cheruvandoor, Kottayam. Her area of interest is phytochemistry.

Publications

Publication Type: Journal Article

Year of Publication Title

2019

A. J. Nair, Raju, J., K, A. G., Kumar, A. A., and Sreesha N. Nair, “Bicosome: A versatile technology in biomedicine and dermopharmacy”, International Journal of Research in Pharmaceutical Sciences, vol. 10, pp. 186-195, 2019.[Abstract]


Bicosomes opened a new chapter in vesicular drug delivery system which immensely contributed to the development of pharmaceutical research. They are defined as bicelles encapsulated in liposomal vesicular structure. One of the peculiar characteristics of bicosomes lies in its distinctive ability to maintain the morphology without any structural changes. They preserve and isolate bicelles from environments with high water contents. This drug delivery system has remarkable stability over temperature changes, in highly diluted media and also an effective permeability modulator for an effective transdermal drug delivery system. This vesicular system becomes a new application for the delivery of the drug through the skin. They are prepared by thin film hydration technique. Unique structures of bicosomes are small enough to pass through stratum corneum of the skin without any damage to tissues and cause structural transformation. This helps to hold the bicosomes between the skin layers and allows slow drug delivery. The capacity of these systems to regenerate skin barrier function and target specific action on skin layers finds its usefulness in the dermatological field. Thus bicosome technology is a versatile platform that can be applied in different skin disorders and appear to be smart nanosystems with great potential in biomedicine and dermopharmacy. © 2018 Pharmascope Publications. All rights reserved. More »»

2019

S. Shefrin, Sreelaxmi, C. S., Joseph, S., and Sreesha N. Nair, “A glance preface and novel approaches for the efficient treatment of a migraine”, International Journal of Research in Pharmaceutical Sciences, vol. 10, pp. 282-297, 2019.[Abstract]


The reviewing of a migraine mainly aimed to analyze the incessant paroxys-mal neurological ailment characterized by moderate to severe head throbbing. The review points out the basic pathophysiology and different types of migraine as well as some of the promising newer antimigraine therapeutic options. The various biomarkers in CSF, as well as blood, are used as standards to diagnose the condition. The triptans released during the 1990s were the initial class of drugs used for acute treatment of migraine. The other conventional therapies offer especially as oral formulations are not exquisitely appropriate for migraineurs having severe nausea and vomiting with reduced gastric absorption. The unmet clinical needs were rapidly advanced, and development of novel drug delivery system ensured better kinetic and dynamic characteristics. The newer drug regimens were more based and targeted on the neurotransmitters directly in involved in the pathophysiology of migraine by utilizing exceptionally confined delivery systems. These include a breath activated the system, transdermal patch, oral inhalers where lower and safer doses of the drug were utilized. Such systems were having improved patient compliance and offered non-invasive route of drug administration that could be suitably substituted by oral medications. The disease disabled the quality of life of patients and also had an abundant effect in the daily activities especially for women. Thus the various nanotechnical approaches are used as novel treatment methods for better and enhanced profiling of drug molecules. © 2018 Pharmascope Publications. All rights reserved.

More »»

2019

A. P, Sreesha N. Nair, and Ambika, “Wound healing activity of plants from the convolvulaceae family”, Advances in Wound Care, vol. 8, pp. 28-37, 2019.[Abstract]


Significance: Compounds derived from plants are gaining importance for the treatment of several diseases. Many plants from the Convolvulaceae family contain compounds that have demonstrated wound healing and antidiabetic activity. Such compounds can be effectively used as a part of treatments to promote wound healing in diabetics and used in combination with antimicrobial therapy to reduce the likelihood of drug resistance and allergic reactions. Novel strategies for developing herbal formulations such as nanoparticles and adhesive patches can improve the delivery of plant-based therapeutic agents. Recent Advances: Studies have confirmed the antidiabetic and wound healing activities of Merremia tridentata, Argyreia speciosa, and Ipomoea batatas, whereas Evolvulus alsinoides, Evolvulus nummularius, Argyreia cuneata, and Ipomoea carnea have wound healing activity. Critical Issues: Drug resistance is a major problem associated with antimicrobial therapy and can affect wound healing processes. Phytoconstituents can facilitate healing processes and reduce reliance on antibiotics. Future Directions: Plants from the Convolvulaceae family have had frequent traditional uses, and all plants selected for this study have antimicrobial, antidiabetic, and wound healing properties. Detailed phytochemical studies of these plants can help develop novel wound healing therapies. © 2019 Mary Ann Liebert, Inc., publishers. More »»

2017

P. Athira and Sreesha N. Nair, “Pharmacognostic review of medicinal plant Aerva lanata”, Journal of Pharmaceutical Sciences and Research, vol. 9, pp. 1420-1423, 2017.[Abstract]


Recently medicinal plants are used to prepare many medicines. Aerva lanata is a medicinal plant used for many purposes. Aerva lanata is also known as knot grass is prostate herb in family Amaranthaceae. It branched and found wild in India. It is a traditional plant in India used for many diseases like anti diuretic, infections, cough, antidote, emollient, skin infections etc… And it has many pharmacological properties like antibacterial, antioxidant, antidiuretic, urolithiasis etc… This review is about the Pharmacognostic study include morphology, microscopy, chemical constituents, pharmacological activity of Aerva lanata. © 2017, Pharmainfo Publications. All rights reserved.

More »»

2017

A. Uthaman and Sreesha N. Nair, “A review on ten sacred flowers in Kerala: Dasapushpam”, Research Journal of Pharmacy and Technology, vol. 10, 2017.[Abstract]


The ten sacred flowers constitute the group dasapushpam. These ten favorable herbs are used in ayurvedic system of medicine and it possesses tremendous therapeutic and potential benefits. It includes different flowers with different characters. These flowers are comes under different families like Amaranthaceae, Oxalidaceae, Sapindoideae, Asteraceae, Convolvulaceae, Poaceae, Hypoxidaceaeetc which possess divine power. It deals with activities such as anti-inflammatory, antimicrobial, anticancer, antifungal, antipsychotic, anti-rheumatic, antiarrhythmic, antidiarrheal, anthelmintic, anti-diabetic etc. It provides a well-established traditional system of medicine. Moreover they give therapeutic benefit with no side effects. The main objective of this review to provide general information about these herbs and their therapeutic values. © 2017, Research Journal of Pharmacy and Technology. All Rights Reserved.

More »»

2017

Sreesha N. Nair, Varghese, A., Meenu, B., Rejimon, G., and Neeraja, E. D., “Comparative evaluation of Coriandrum sativum Linn. And Apium graveolens for Antimicrobial activity”, Research Journal of Pharmacy and Technology, vol. 10, pp. 1-4, 2017.[Abstract]


This main objective of this study is to compare the antimicrobial activity of extracts of Coriandrum sativum Linn. and Apium graveolens Linn. (family Apiaceae). Ethanol was used as organic solvent to prepare the crude extracts from the leaves. Antimicrobial activity of both plant extract were evaluated by agar well disc diffusion method against Streptococcus mutans, Klebsiella pneumonia and Pseudomonas aeroginosa. The ethanolic crude extract of Coriandrum sativum Linn. showed more activity against Streptococcus mutans and that of Apium graveolens Linn. showed more activity against Klebsiella pneumonia and Pseudomonas aeroginosa. In conclusion both these plants can be considered as natural source of antimicrobials therefore will be included in our daily diet. © 2017, Research Journal of Pharmacy and Technology. All rights reserved.

More »»

2016

Sreesha N. Nair, Bindu, K., and R, B. A., “Pharmacognostic evaluation of Drymoglossum heterophyllum-(L)C. Chr”, vol. 8, pp. 7-12, 2016.[Abstract]


Drymoglossum heterophyllum-(L)C.Chr. is an epiphytic fern which is commonly known as Dragon Scales is an important medicinal plant belonging to Pteridaceae family. The leaves are used for many medicinal purposes. This study provides taxonomical, pharmacological and physicochemical details helpful in laying down standardization and pharmacopoeial parameters. The diagnostic characters are aseptate trichomes anomocytic stomata, reddish brown sclerenchyma and thick walled cuticle. The physicochemical studies revealed total moisture content(8.65%), total ash value(7.75%), water soluble ash(4.42%), acid insoluble ash value(3.466%), Alcohol soluble extractive(4.157 %) water soluble extractive value(7.85%), Crude fibre content(18.18%) and total chlorophyll content (0.449/g). © 2016, Journal of Chemical and Pharmaceutical Research. All rights reserved.

More »»
Faculty Research Interest: