Project

Photo switchable Azobenzene Conjugated Matrices for Affinity Chromatography: Synthesis, Characterization and Studies

There are reports on derivatives of azobenzene that exhibit light-triggered association of Bovine Serum Albumin. To this end, an azobenzene-triazine conjugate was prepared by reacting Disperse Orange 3 dye with trichlorotrizaine. This intermediate was then conjugated to the biopolymer chitosan by a facile nucleophilic substitution. It was presumed that the interactions between the azobenzene moiety and albumin would lead to the development of new matrices which can bind albumin effectively.