Bacteria such as <em>Listeria monocytogenes</em> recruit cellular machinery to move in and between cells. Understanding the mechanism of motility, including force and torque generation and the resultant displacements, holds keys to numerous applications in medicine and biosensing. In this work, a simple back-of-the-envelope calculation is presented to illustrate that a biomechanical model of actin-based motility of a rigid surface through persistently attached filaments propelled by affinity-modulated molecular motors can produce a right-handed helical trajectory consistent with experimental observations. The implications of the mechanism to bacterial motility are discussed.
cited By 0; Conference of 56th DAE Solid State Physics Symposium 2011 ; Conference Date: 19 December 2011 Through 23 December 2011
M. Rangarajan, “Actin-based motility of Listeria: Right-handed helical trajectories”, SOLID STATE PHYSICS: PROCEEDINGS OF THE 56TH DAE SOLID STATE PHYSICS SYMPOSIUM 2011, vol. 1447. AIP Publishing, pp. 165-166, 2012.