Publication Type:

Journal Article

Source:

International Journal of Pharmacy and Technology, Volume 3, Number 2, p.2560-2564 (2011)

URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-79960113657&partnerID=40&md5=cf9feaa16c143e7884b54c3de37efb23

Keywords:

alkaloid, antineoplastic activity, antineoplastic agent, article, breast cancer, cancer inhibition, carbohydrate, cell strain MCF 7, cell viability, concentration response, controlled study, drug cytotoxicity, drug potency, drug screening, flavonoid, Helicteres isora, Helicteres isora extract, human, human cell, phytochemistry, plant extract, Sterculiaceae, tannin derivative, unclassified drug

Abstract:

Helicteres isora belongs to the family sterculiaceae is an ayurvedic herb.it is distributed widely in forest throughout india and are commonly known as east india screw tree spi_sup1spii_sup. Is a medicinally important sub-deciduous shrub or small tree.almost all parts of the plant are used in traditional medicinal system for curing various diseases. its fruit,Root and bark possess significant antidiabetic. Antioxidant,Antimicrobial and hypolipidemic activity. the fruit of helicterusisora after collection,Authentication and drying was extracted with chloroform using soxhlet extractor.the present study was aimed to determine the preliminary phytochemical evaluation and cytotoxicity study of the chloroform extract of helicteres isora on MCF - 7 cell line (human breast cancer) by MTT assay method. the preliminary phytochemical evaluation showed the presence of carbohydrates,Flavonoids,Tannins and alkaloidsspi_sup2spii_sup.its cytotoxic evaluation showed a potent action against to MCF - 7 (michigan cancer foundation - 7) cell line.

Notes:

cited By (since 1996)0

Cite this Research Publication

E. Varghese, S. Narayanan, S., Gopal, R. V., Nair, A., Chittethu, A. B., and Anson, T. A., “Aticancer activity of chloroform extract of Helicteres ISORA”, International Journal of Pharmacy and Technology, vol. 3, pp. 2560-2564, 2011.