Publication Type:

Journal Article


International Journal of Biological Macromolecules, Volume 45, Number 2, p.135 - 139 (2009)



Bioactivity, chitosan, Grafting, Metal uptake studies, XRD studies


Carboxymethyl chitosan-graft-d-glucuronic acid (CMCS-g-d-GA) was prepared by grafting d-GA onto CMCS in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and then the membranes were made from it. In this work, the bioactivity studies of CMCS-g-d-GA membranes were carried out and then characterized by SEM, CLSM, XRD and FT-IR. The CMCS-g-d-GA membranes were found to be bioactive. The adsorption of Ni2+, Zn2+and Cu2+ ions onto CMCS-g-d-GA membranes has also been investigated. The maximum adsorption capacity of CMCS-g-d-GA for Ni2+, Zn2+and Cu2+ was found to be 57, 56.4 and 70.2mg/g, respectively. Hence, these membranes were useful for tissue engineering, environmental and water purification applications.

Cite this Research Publication

Dr. Jayakumar Rangasamy, Rajkumar, M., Freitas, H., Kumar, P. T. Sudheesh, Nair, S. V., Furuike, T., and Tamura, H., “Bioactive and metal uptake studies of carboxymethyl chitosan-graft-d-glucuronic acid membranes for tissue engineering and environmental applications”, International Journal of Biological Macromolecules, vol. 45, pp. 135 - 139, 2009.