Publication Type:

Journal Article

Source:

Carbohydrate Polymers, Elsevier Ltd, Volume 198, p.385-400 (2018)

URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049096110&doi=10.1016%2fj.carbpol.2018.06.086&partnerID=40&md5=3e64675d9a70ce96bba2bb9fafccc406

Keywords:

Bioprinting, Carrageenan hydrogels, Cell delivery, Cell engineering, Controlled drug delivery, Drug delivery, Drug delivery applications, Drug products, Hydrogels, Pharmaceutical drug formulations, Physio-chemical properties, Scaffolds (biology), Targeted drug delivery, Tissue, tissue engineering, Tissue-engineered scaffolds, Wound healing

Abstract:

Carrageenan is a class of naturally occurring sulphated polysaccharides, which is currently a promising candidate in tissue engineering and regenerative medicine as it resemblances native glycosaminoglycans. From pharmaceutical drug formulations to tissue engineered scaffolds, carrageenan has broad range of applications. Here we provide an overview of developing various forms of carrageenan based hydrogels. We focus on how these fabrication processes has an effect on physiochemical properties of the hydrogel. We outline the application of these hydrogels not only pertaining to sustained drug release but also their application in bone and cartilage tissue engineering as well as in wound healing and antimicrobial formulations. Administration of these hydrogels through various routes for drug delivery applications has been critically reviewed. Finally, we conclude by summarizing the current and future outlook that promotes the seaweed-derived polysaccharide as versatile, promising biomaterial for a variety of bioengineering applications. © 2018 Elsevier Ltd.

Notes:

cited By 0

Cite this Research Publication

R. Yegappan, Selvaprithiviraj, V., Amirthalingam, S., and Dr. Jayakumar Rangasamy, “Carrageenan Based Hydrogels for Drug Delivery, Tissue Engineering and Wound Healing”, Carbohydrate Polymers, vol. 198, pp. 385-400, 2018.