Publication Type:

Journal Article


International Journal of Pharmaceutical Sciences Review and Research, Volume 44, Issue 1, p.27-29 (2017)



Acute cellular Rejection (ACR), Antibody mediated Rejection (AMR)., End stage renal disease (ESRD), Simultaneous pancreas kidney transplantation (SPK), Tacrolimus (TAC)


Simultaneous pancreas kidney transplantation (SPK) performed as the universal treatment for patients who have type 1 diabetes mellitus and ESRD. Here we present a case series of 4 SPK cases, successfully performed. Successful SPK transplantation increase patient survival enhances quality of life, and decline diabetic complications. Suitability of SPK transplantation is dependent upon patient selection including their age and comorbidities. All patients received transplanted organ from cadaveric donor. This article discusses with immunosuppression consists of induction and maintenance therapy. Allograft dysfunction is a serious issue, after transplantation of kidney. Management of ACR and AMR has been discussed in the fourth case.

Cite this Research Publication

D. S. Raju, Sudhindran, S., and Roshni P. R., “A case series on Simultaneous Pancreas Kidney transplantation”, International Journal of Pharmaceutical Sciences Review and Research, vol. 44, no. 1, pp. 27-29, 2017.