One of the biggest challenges the world face today is the mortality due to Cancer. One in four of all diagnosed cancers involve the lung cancer. The lung cancer remains the most common cancer-related cause of death both in developed and developing countries due to inhaling cancer-causing substance such as tobacco. Screening test help doctors to find and detect cancer at early stages. Several methods such as MRI, chest-X rays, CT Scan, etc., are available for screening tests. For developing countries, the cost involved for early detection with the available methods is not affordable. This paper presents a novel low cost method to detect and classify lung glandular cells as benign or malignant (Cancer cells) using conventional pap stained sputum cytology images. The microscopic sputum images are preprocessed and analysis is restricted to cellular regions. For segmentation we use multiple color spaces and clustering algorithms: K-Means and Fuzzy C-Means. Scale Space based Catastrophe points are used as features and are classified using Support Vector Machine (SVM). We successfully classified the glandular cells as benign or malignant cells with an accuracy of 78.61%.
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Da Venkataraman, Suganthi, Jb, Kecheril, ScSajith, and Sujathan, Kd, “Classification of lung glandular cells for early detection of cancer using multiple color spaces and scale space catastrophe features”, Life Science Journal, vol. 10, pp. 2971-2980, 2013.