Publication Type:

Journal Article


Indian Journal of Clinical Biochemistry, Volume 24, Number 2, p.155-158 (2009)



adult, alanine aminotransferase, article, aspartate aminotransferase, bilirubin, bilirubin blood level, diabetes mellitus, Fatty Liver, female, human, hyperlipidemia, India, major clinical study, male, non alcoholic fatty liver disease, obesity


Non-alcoholic fatty liver disease and its more aggressive form, non-alcoholic steatohepatitis are entities that are becoming more and more interesting to the medical community in general. A total of 93 Non-alcoholic fatty liver disease patients (64 male and 29 female) within the age range between 28 to 63 years were studied. All of them showed elevated alanine aminotransferase level (104.07 ± 56.04). Aspartate aminotransferase level (58.13 ± 31.96) was elevated more than its normal level in 82% cases and AST to ALT ratio was found 0.59 ± 0.26. Predisposing factors were diabetes mellitus (37%), obesity (13%) and hyperlipidemia (41%). In addition, 32% of the subjects were overweight.18% of the patients had elevated serum bilirubin. Our findings recommend a lower cutoff value than suggested by the World Health Organization for overweight and obesity among this racial-ethnic group. © 2009 Association of Clinical Biochemists of India.


cited By 1

Cite this Research Publication

D. M. Vasudevan, Das, S. K., Mukherjee, S., Pandey, G., and Balakrishnan, V., “Clinicopathological spectrum of non-alcoholic fatty liver disease among patients in Kerala”, Indian Journal of Clinical Biochemistry, vol. 24, pp. 155-158, 2009.