Publication Type:

Journal Article


Indian Journal of Radiology and Imaging, Volume 20, Number 3, p.192-194 (2010)



Acute Disease, adjuvant chemotherapy, adult, anamnesis, article, case report, clinical feature, diffusion weighted imaging, fluorouracil, folinic acid, human, leukoencephalopathy, male, muscle weakness, nuclear magnetic resonance imaging, periorbital edema, rectum carcinoma, speech disorder


Acute toxic leukoencephalopathy may be caused by endogenous or exogenous toxins. It may reverse clinically if the offending agent is withdrawn or the underlying condition is treated. However, demonstration of reversibility on imaging, especially with diffusion-weighted MRI, has been reported only very recently. We report two such cases.


cited By (since 1996)1

Cite this Research Publication

S. Sivasubramanian, S. Moorthy, Sreekumar, K. P., and Kannan, R. R., “Diffusion-weighted magnetic resonance imaging in acute reversible toxic leukoencephalopathy: A report of two cases”, Indian Journal of Radiology and Imaging, vol. 20, pp. 192-194, 2010.