Publication Type:

Journal Article

Source:

International Journal of Pharmacy and Pharmaceutical Sciences, International Journal of Pharmacy and Pharmaceutical Science, Volume 7, Number 11, p.389-391 (2015)

URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84946558148&partnerID=40&md5=4df54a4e802fb220c9030917eb81cf3b

Keywords:

adult, aged, ampicillin, antibiotic agent, article, azithromycin, beta 2 adrenergic receptor stimulating agent, budesonide, Candida albicans, cefoperazone, cefotaxime, ceftriaxone, cephalosporin, cholinergic receptor blocking agent, chronic obstructive lung disease, corticosteroid, coughing, drug utilization, dyspnea, female, fluticasone, gentamicin, human, hydrocortisone, hypertension, ipratropium bromide, levalbuterol, levofloxacin, macrolide, major clinical study, male, methylprednisolone, methylxanthine, middle aged, mucolytic agent, penicillin derivative, penicillin G, piperacillin, prednisolone, Pseudomonas aeruginosa, quinoline derived antiinfective agent, retrospective study, Sputum, sulbactam, tazobactam, tiotropium bromide, unindexed drug, very elderly

Abstract:

Objective: Drug utilization studies provide useful insights into the current prescribing practices. In view of this, the present study was designed to establish the drug utilization pattern in hospitalized chronic obstructive pulmonary disease (COPD) patients. Methods: In this retrospective study, all patient data relevant to the study were obtained by examination of patient’s medical records and hospital information system. Results: A total of 237 patients with acute exacerbation were evaluated. The population predominantly consisted of males (92.4%) and most of the patients were in the age group of 61 to 70 y (39.7%). Cough, sputum production and dyspnea were observed in 88.2%, 80.6% and 37.6% patients, respectively. Hypertension (49.4%) was the most common co-morbidity. Candida albicans (16%) and Pseudomonas aeruginosa (4.6%) were the most common microorganisms isolated from sputum samples. Majority of the patients were on multidrug therapy during both hospital stay (98.7%) and at the time of discharge (99.6%). During hospital stay, the most commonly prescribed drugs were ipratropium (91.6%) and levosalbutamol (88.2%); antibiotics and systemic corticosteroids were received by 96.2% and 83.1% patients, respectively. At discharge, antibiotics, inhaled corticosteroids, methyl xanthines, long acting beta-2 agonist and tiotropium were received by 94.1%, 93.7%, 92.4%, 86.1% and 56.5% patients, respectively. Conclusion: The prescribing trend observed at our hospital appears to be in concordance with the current guidelines for the management of COPD patients. © 2014 All Rights Reserved.

Notes:

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Cite this Research Publication

Aa Unni, Jayaprakash, A. Ka, Yadukrishnan, M. Cb, and P.c Uma Devi, “Drug utilization pattern in chronic obstructive pulmonary disease inpatients at a tertiary care hospital”, International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, pp. 389-391, 2015.