Publication Type:

Journal Article


Indian journal of experimental biology, National Institute of Science Communication and Information Resources, Volume 47, Number 7, p.608–610 (2009)


Ethanol intoxication resulted in high extent of lipid peroxidation, and reduction in antioxidant defenses (decreased GSH, GSH/GSSG ratio, and catalase, SOD and GPx activities) and (Na+/K+)-ATPase activity in kidney. Alpha-tocopherol treatment effectively protected kidney from ethanol induced oxidative challenge and improved renal (Na+/K+)-ATPase activity. Ethanol induced oxidative stress in the kidney and decreased (Na+/K+)-ATPase activity could be reversed by treatment with ascorbic acid.

Cite this Research Publication

M. Mailankot, .Jayalekshmi, H., Chakrabarti, A., Alang, N., and Vasudevan, D. M., “Effect of Alpha-Tocopherol Supplementation on Renal Oxidative Stress and Na+/K+-Adenosine Triphosphatase in Ethanol Treated Wistar Rats.”, Indian journal of experimental biology, vol. 47, pp. 608–610, 2009.