Effect of Alpha-Tocopherol Supplementation on Renal Oxidative Stress and Na+/K+-Adenosine Triphosphatase in Ethanol Treated Wistar Rats.
Publication Type:Journal Article
Source:Indian journal of experimental biology, National Institute of Science Communication and Information Resources, Volume 47, Number 7, p.608–610 (2009)
Ethanol intoxication resulted in high extent of lipid peroxidation, and reduction in antioxidant defenses (decreased GSH, GSH/GSSG ratio, and catalase, SOD and GPx activities) and (Na+/K+)-ATPase activity in kidney. Alpha-tocopherol treatment effectively protected kidney from ethanol induced oxidative challenge and improved renal (Na+/K+)-ATPase activity. Ethanol induced oxidative stress in the kidney and decreased (Na+/K+)-ATPase activity could be reversed by treatment with ascorbic acid.
Cite this Research Publication
Related Research Publications
- Effect of alpha-tocopherol supplementation on renal oxidative stress and Na+/K+-adenosine triphosphatase in ethanol treated wistar rats
- Effect of lecithin with vitamin-b complex and tocopheryl acetate on long term effect of ethanol induced immunomodulatory activities
- Experimental therapeutic intervention with alpha tocopherol in ethanol induced testicular injuries in rats
- Long-term ethanol consumption leads to lung tissue oxidative stress and injury
- Alcohol induced effects on kidney