Dipyrromethene-Cu(II) derivatives possessing two dodecane alkyl chains have been used for the modification of gold electrodes. Electroactive host molecules have been incorporated into a lipophilic dodecanethiol SAM deposited onto gold electrodes through hydrophobic and van der Waals interactions (embedment technique). The presence of dipyrromethene-Cu(II) redox centers on the electrode surface was proved by cyclic voltammetry and Osteryoung square-wave voltammetry. The Au electrodes incorporating redox active Cu(II)-dipyrromethene SAMs were used for the direct voltammetric determination of paracetamol in human plasma.
Dr. Beena S., Izabela Grzybowska, Czesława Orlewska, Jerzy Radecki, Wim Dehaen, Krishnapillai Girish Kumar, and Hanna Radecka, “Electroactive Dipyrromethene-Cu(II) Monolayers Deposited onto Gold Electrodes for Voltammetric Determination of Paracetamol”, Electroanalysis, vol. 20, pp. 2317–2323, 2008.