Publication Type:

Journal Article


Annals of Pediatric Cardiology, Volume 6, Number 2, p.121-125 (2013)



adolescent, age distribution, article, artificial ventilation, body weight, child, convalescence, erythrocyte parameters, Fallot tetralogy, female, heart ventricle septum defect, hematocrit, hemoglobin, hemoglobin blood level, hospitalization, human, infant, major clinical study, male, mean corpuscular hemoglobin, mean corpuscular volume, outcome assessment, postoperative complication, postoperative period, preschool child, red cell distribution width, retrospective study, school child, surgical infection


{Objective: To study the impact of red cell distribution width (RDW) on postoperative recovery after correction of Tetralogy of Fallot (TOF). Background: Increased RDW indicates dysregulated erythropoiesis and predicts survival in critical illnesses that include idiopathic pulmonary artery hypertension and chronic heart failure. Myocardial injury and oxidative stress induced by cardiopulmonary bypass potentially contribute to prolonged recovery in post TOF repair patients. Materials and Methods: Retrospective analysis of data on 94 consecutive children with TOF undergoing corrective repair (January 2010-March 2011) was done. RDW was higher for the study population when compared to acyanotic patients with ventricular septal defect (17.7 ± 3.7 vs. 16.2 ± 4.2; P < 0.001). The mean RDW obtained from 100 separate age-, sex-, and weight-matched TOF patients (17.8) was chosen as a cut-off. Of 93 survivors (median age: 12 (4-204) months, weight: 8.6 (3.2-70) kg), 29 patients with higher RDW (> 17.8) had a longer ICU stay (155.6 ± 71.3 vs. 122.4 ± 61.3 hours


cited By (since 1996)0

Cite this Research Publication

Sa Kumar, Sudhakar, Aa, Mohan, Ma, Balachandran, Rb, Raj, Bc, Sumangala, S. Gc, and Kumar, RaKrishna, “Elevated red cell distribution width is associated with delayed postoperative recovery after correction of Tetralogy of Fallot”, Annals of Pediatric Cardiology, vol. 6, pp. 121-125, 2013.