Publication Type:

Journal Article

Source:

Applied Physics Letters, Volume 99, Number 16 (2011)

URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-80155137375&partnerID=40&md5=c247c48c91d739f4588e3fa080f3bebf

Keywords:

Anti-inflammatory activity, Anti-proliferative, atomic force microscopy, cell interaction, Cell membranes, curcumin, Cytology, Diseases, Drug development, Drug Interactions, Enhanced uptake, molecular biology, Nasopharyngeal cancer, Real time

Abstract:

Recent studies in drug development have shown that curcumin can be a good competent due to its improved anticancer, antioxidant, anti-proliferative, and anti-inflammatory activities. A detailed real time characterization of drug (curcumin)-cell interaction is carried out in human nasopharyngeal cancer cells using atomic force microscopy. Nanocurcumin shows an enhanced uptake over micron sized drugs attributed to the receptor mediated route. Cell membrane stiffness plays a critical role in the drug endocytosis in nasopharyngeal cancer cells.

Notes:

cited By (since 1996)4

Cite this Research Publication

R. Prasanth, Nair, G., and Girish C. M., “Enhanced Endocytosis of Nano-curcumin in Nasopharyngeal Cancer Cells: An Atomic Force Microscopy Study”, Applied Physics Letters, vol. 99, 2011.

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