Publication Type:

Journal Article


Indian Journal of Clinical Biochemistry, Volume 13, Number 2, p.126-128 (1998)



In a pilot study with five oral cancer patients undergoing radiotherapy (RT) three were given Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) as a protective agent to reduce the mucosal inflammation during radiotherapy. The myeloperoxidase (MPO) enzyme activity in WBC was quantitated. The three patients snowed a significant increase in the MPO activity when compared with two untreated controls indicating the efficacy of GM-CSF as a protective agent. It is suggested that further detailed studies with larger number of patients would be useful.


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Cite this Research Publication

N. Ananth, ,, Vasudevan, D. M., Souza, V. D., Rao, A. V., and Nambiar, D., “Enhancement of myeloperoxidase activity in wbcs in oral cancer patients treated with granulocyte macrophage colony stimulating factor (GM-CSF) - A pilot study”, Indian Journal of Clinical Biochemistry, vol. 13, pp. 126-128, 1998.