Publication Type:

Journal Article

Source:

Pakistan Journal of Pharmaceutical Sciences, Volume 23, Issue 2, p.232-235 (2010)

URL:

https://www.ncbi.nlm.nih.gov/pubmed/20363705

Abstract:

Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulation CZ2 (1:1:3). The hardness and friability of all the formulations were found to be within the standard limit for orodispersible tablets. Disintegration time was found to be rapid in formulation CZ2 (1:1:3).The in vitro dissolution time was found to be 100% in 11 minutes for the formulation CZ2 (1:1:3).

Cite this Research Publication

S. Subramanian, Sankar, V., Asha Asokan Manakadan, Ismail, S., and Andhuvan, G., “Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet”, Pakistan Journal of Pharmaceutical Sciences, vol. 23, no. 2, pp. 232-235, 2010.

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