Plumbagin, a napthoquinone from the plant Plumbago zeylanica, delayed pupation when topically applied to newly moulted final instars of the leaf eating caterpillar Opisina arenosella Walker (Lepidoptera: Oecophoridae). Pupae from treated larvae emerged into non-viable adults and had abnormalities such as deformed wings and shrunken abdomens; they also died much before the control insects. The results suggest that plumbagin interferes with the process of development and ecdysis of the insect.
M. A. Suresh Kumar and Banerji, A., “Growth Disruption in Opisina arenosella Walker by Plumbagin, A Naturally Occurring Insect Growth Regulator”, International Journal of Tropical Insect Science, vol. 22, pp. 321–322, 2002.