Publication Type:

Journal Article


Pharmacologyonline, Volume 2, p.115-127 (2007)



animal experiment, animal model, animal tissue, antilipemic agent, aorta, aqueous solution, article, atherogenesis, atheroma, atherosclerosis, basil, cholesterol blood level, cholesterol diet, controlled study, drug dose comparison, drug efficacy, drug isolation, drug solution, high density lipoprotein cholesterol, histopathology, lipid, lipid blood level, lipid liver level, low density lipoprotein cholesterol, male, nonhuman, Ocimum sanctum extract, rabbit, triacylglycerol, triacylglycerol blood level, very low density lipoprotein cholesterol


Effect of aqueous extract of Ocimum sanctum on experimentally induced atherosclerosis in rabbits has been studied. Feeding 0.5g cholesterol/ day for 45days has induced atheroma in control group. A dose dependant reduction in atheroma in Ocimum sanctum extract treated groups was noticed. Ocimum sanctum extract treatment brought down the lipid levels of blood, liver and aortic tissue. Along with strong hypolipidemic effect, Ocimum sanctum inhibited the atherogenesis.


cited By 2

Cite this Research Publication

D. M. Vasudevan, Samak, G., Rao, M. S., and Kedlaya, R., “Hypolipidemic efficacy of Ocimum sanctum in the prevention of atherogenesis in male albino rabbits”, Pharmacologyonline, vol. 2, pp. 115-127, 2007.