Effect of aqueous extract of Ocimum sanctum on experimentally induced atherosclerosis in rabbits has been studied. Feeding 0.5g cholesterol/ day for 45days has induced atheroma in control group. A dose dependant reduction in atheroma in Ocimum sanctum extract treated groups was noticed. Ocimum sanctum extract treatment brought down the lipid levels of blood, liver and aortic tissue. Along with strong hypolipidemic effect, Ocimum sanctum inhibited the atherogenesis.
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D. M. Vasudevan, Samak, G., Rao, M. S., and Kedlaya, R., “Hypolipidemic efficacy of Ocimum sanctum in the prevention of atherogenesis in male albino rabbits”, Pharmacologyonline, vol. 2, pp. 115-127, 2007.