Publication Type:

Journal Article

Source:

International Journal of Drug Delivery, Advanced Research Journals, Volume 7, Issue 1, Number 1, p.27-31 (2015)

URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941283456&partnerID=40&md5=44c9e3781a940cfd0b406e8e7177c470

Abstract:

Computational modeling of polymeric nanoparticles as drug carriers have been extensively studied due to their varied functionalities, tunable structures and the capability of controlled drug release. Nano particulate polymeric drug delivery systems enable a cell specific targeting with negligible side effects and drug release based on change in physiological conditions. Eight common polymers are modeled and the various properties have been predicted. ADMET, QSAR, thermodynamic and electronic properties have been predicted and compared using SAR as well as quantum mechanical density functional methods. Comparison of the predicted properties suggests that chitosan, which is a natural polymer and has some advantages over others is a promising drug carrier candidate for tumor. © 2014, Advanced Research Journals. All rights reserved.

Notes:

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Cite this Research Publication

A. E. Silviya, Kavitha, G., K. Kutty, N., and Namboori, P. K. Krishnan, “Insilico modeling of chitosan as a drug delivery system”, International Journal of Drug Delivery, vol. 7, no. 1, pp. 27-31, 2015.