Aloe vera has an immense role as a natural fighter against all kinds of infection. This is an effective wound healing activator and an efficient anti-oxidant to all type of digestion related problems, arthritis, stress, diabetes, cancer and AIDS. The present study attempts to reveal the multi therapeutic properties of Aloe vera by computational analysis. The interaction analysis of the some of the derived phytochemicals with various targets including proteins involved in Alzheimer's and its role in curing such ailments has been examined. The interaction energy result suggests that Aloe emodin, Emodin, Aloin, Rhein, Coumarin, and Acemannan have an effective role in curing the pandemic conditions. The interaction anlaysis of Acemannan is greatest among all the results, suggesting that this ligand enhance the wound healing capacity. Acemannan was found to be a potent inhibitor of HIV virus replication. Anti inflammatory diseases like arthritis, asthma, hay fever can be cured to some extent by using Emodin, which is an efficient anti-inflammatory agent. Aloe Emodin can be used as an activator of apoptotic pathway in cancer cells as well as an anti sepsis agent. © 2011 IEEE.
cited By (since 1996)0; Conference of org.apache.xalan.xsltc.dom.DOMAdapter@532e7964 ; Conference Date: org.apache.xalan.xsltc.dom.DOMAdapter@1023bee6 Through org.apache.xalan.xsltc.dom.DOMAdapter@1ac9f651; Conference Code:84785
S. Ca Pillai, P. K. Krishnan Namboori, Kumar, N. C. Ab, Gopal, K. Vb, Kumar, A. Sb, and Bharath, Pb, “Investigating multi target drug action of aloe vera using computational analysis”, in Proceedings - 2011 2nd National Conference on Emerging Trends and Applications in Computer Science, NCETACS-2011, Shillong, 2011, pp. 174-177.