Publication Type:

Journal Article

Source:

Asian J Pharm Clin Res, Volume 5, Number 4, p.150–152 (2012)

URL:

http://www.ajpcr.com/Vol5Issue4/1313.pdf

Keywords:

ICH, Silodosin, UV-vis spectroscopy, Validation

Abstract:

The present study describes a simple, accurate, precise and cost effective UV-VIS Spectrophotometric method for the estimation of Silodosin, a selective antagonist of alpha-1 adrenoreceptors used for reliving the symptoms of enlarged prostste, in bulk and pharmaceutical dosage form. The solvent used is methanol and the λ max or the absorption maxima of the drug was found to be 269nm. A linear response was observed in the range of 5-50μg/ml with regression coefficient of 0.994. The method was then validated for different parameters as per ICH guidelines. This method can be used for the determination of Silodosin in quality control of formulation without interference of the excipient

Cite this Research Publication

Dr. Aneesh T. P. and Rajasekaran, A., “Method Development and Validation for the Estimation of Sildosin in Bulk And Pharmaceutical Dosage Forms Using UV-Vis Spectrophotometry”, Asian J Pharm Clin Res, vol. 5, pp. 150–152, 2012.

207
PROGRAMS
OFFERED
6
AMRITA
CAMPUSES
15
CONSTITUENT
SCHOOLS
A
GRADE BY
NAAC, MHRD
8th
RANK(INDIA):
NIRF 2018
150+
INTERNATIONAL
PARTNERS