Publication Type:

Journal Article

Source:

International journal of biological macromolecules, Elsevier, Volume 67, p.279–288 (2014)

URL:

http://www.sciencedirect.com/science/article/pii/S0141813014002098

Keywords:

Chitin; PLGA; Composite nanogels; Microbial and cellular imaging; Hyperthermia

Abstract:

Cyto-compatible, 80 nm sized chitin/PLGA composite nanogels (chit/PLGA-comp NGs) were prepared by regeneration method and characterized. The multifaceted chit/PLGA-comp NGs were surface modified with Au, Fe3O4, CdTe/ZnTe-QDs and umbelliferone, respectively. 185 nm sized Au-chit/PLGA-comp NGs, 170 nm sized QD-chit/PLGA-comp-NGs and 160 nm sized Fe3O4-chit/PLGA-comp-NGs showed RF heating. The QD-chit/PLGA-comp-NGs and 180 nm sized umb-chit/PLGA-comp-NGs were well uptaken by Escherichia coli, Staphylococcus aureus and Candida albicans. The chit/PLGA-comp NGs could be useful for microbial monitoring and RF application for cancer therapy. The preliminary data showed that multifaceted chit/PLGA-comp-NGs could be useful for hyperthermia for cancer treatment and microbial labelling and imaging.

Notes:

cited By 4

Cite this Research Publication

S. N Rejinold, Dr. Raja Biswas, Chellan, G., and Jayakumar, R., “Multifaceted chitin/poly (lactic-co-glycolic) acid composite nanogels”, International journal of biological macromolecules, vol. 67, pp. 279–288, 2014.

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