Scaffold proteins support a variety of key processes during animal development. Mutant mouse for the MAGUK protein Discs large 5 (Dlg5) presents a general growth impairment and moderate morphogenetic defects.
Dr. Parvathy Venugopal, Veyssière, H., Couderc, J. - L., Richard, G., Vachias, C., and Mirouse, V., “Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster”, MC Dev Biol, vol. 20, no. 1, p. 10, 2020.