Publication Type:

Journal Article

Source:

Annals of Transplantation, International Scientific Information, Inc., Volume 22, p.499-506 (2017)

URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029584573&doi=10.12659%2fAOT.904350&partnerID=40&md5=21d31f1cc7caf4c6b5c16d2878c334dd

Keywords:

adult, alcohol consumption, article, bacterial peritonitis, blood culture, body mass, C reactive protein, cardiovascular disease, diabetes mellitus, diagnostic test accuracy study, DORMAT Score, dyslipidemia, electronic medical record, end stage liver disease, female, hepatobiliary parameters, hepatopulmonary syndrome, hepatorenal syndrome, human, hypertension, intensive care unit, liver transplantation, living donor liver transplantation, major clinical study, male, Model For End Stage Liver Disease Score, patient history of liver transplantation, portal vein thrombosis, preoperative evaluation, procalcitonin, receiver operating characteristic, respiratory tract disease, retrospective study, Sodium

Abstract:

Background: Recipient outcomes in adult living donor liver transplantation depend on various characteristics in both recipient and donor. We aimed to derive a score based upon preoperative characteristics in donor and recipient that could predict the recipient mortality in adult living donor liver transplantation. Material/Methods: Retrospective data of 100 living donor liver transplantation recipients and their respective donors were analyzed for preoperative factors that correlated with recipient mortality. Statistically significant factors were weighted appropriately to derive a regression equation to obtain a donor-to-recipient match (DORMAT) score. This score was applied to 71 patients prospectively and their outcome was analyzed. Results: Donor-recipient match (DORMAT) score, derived using regression analysis of the significant variables was [0.002 (Recipient age) + 0.013 (Recipient BMI) + 0.055 (SBP) + 0.344 (HRS) + 0.022 (Pre-op culture positivity) + 0.01 (Donor age) – 0.639]×100. DORMAT score, when validated to a prospective cohort of 71 adult-to-adult LDLT patients, had a C-statistic (area under ROC curve) of 0.712. The mortality rate was seen to increase with increasing DORMAT score. Conclusions: DORMAT score is a useful clinical decision-making tool to predict recipient mortality in adult living donor liver transplantation. © Ann Transplant, 2017.

Notes:

cited By 0

Cite this Research Publication

R. Babu, Sethi, P., Surendran, S., Dhar, P., Gopalakrishnan, U., Balakrishnan, D., Menon, R. N., Thankamonyamma, B. S., Vayoth, S. O., and Thillai, M., “A new score to predict recipient mortality from preoperative donor and recipient characteristics in living donor liver transplantation (DORMAT score)”, Annals of Transplantation, vol. 22, pp. 499-506, 2017.

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