Publication Type:

Journal Article

Source:

Materials Today: Proceedings, Volume 18, p.5081 - 5086 (2019)

URL:

http://www.sciencedirect.com/science/article/pii/S2214785319326938

Keywords:

Cystamine, Cysteamine, cystinosis, Electrochemical sensor, Voltammetry

Abstract:

A highly sensitive electrochemical sensor was fabricated using disposable pencile graphite electrode for the determination of cysteamine. Electrode characterization was done using scanning electron microscopy and X-Ray diffraction studies. The electrochemical properties of the PGE were studied using cyclic voltammetry and differential pulse voltammetric methods. The oxidation peak of cysteamine was observed at a potential of +0.446 V in 0.1 M NaOH and is attributed to the oxidation of the cysteamine to the dimer cystamine. The fabricated sensor exhibited a linear dynamic range of 10µM-110µM. The sensitivity was found to be 0.4077 µA/µM/cm2, with a detection limit of 4µM. The proposed electrochemical sensor was used for the determination of cysteamine in urine samples with high selectivity..

Cite this Research Publication

R. R, R, K. P., and Dr. Beena S., “A novel disposable pencil graphite electrode for the voltammetric determination of cysteamine”, Materials Today: Proceedings, vol. 18, pp. 5081 - 5086, 2019.