Publication Type:

Journal Article

Source:

Materials Today: Proceedings, Volume 5, Number 8, Part 3, p.16220 - 16225 (2018)

URL:

http://www.sciencedirect.com/science/article/pii/S221478531831068X

Keywords:

Biomarkers, Liver Disorders, Paper Based Device, photolithography, Total Serum Protein

Abstract:

Liver disorders are a widespread health problem and a leading cause of morbidity and mortality in developing countries. The mortality rate due to liver disorders can be reduced significantly by systematic monitoring of proteins that act as liver function biomarkers. This paper demonstrates the design and fabrication of a paper based microfluidic device for the quantification of total protein in blood. The fabrication of microchannels was carried out using wax printing. The total protein concentration in the range of 0 to 14 g dL-1were successfully measured using the fabricated paper device with the lower limit of detection being 0.5 g dL-1. The device also showed excellent specificity and repeatability. Total protein in blood serum samples was tested using the device and the obtained results were validated with conventional laboratory methods.

Notes:

cited By 0; Conference of 2016 International Conference on Advanced Materials, SCICON 2016 ; Conference Date: 19 December 2016 Through 21 December 2016; Conference Code:138807

Cite this Research Publication

P. Dilna, Raveendran, J., John Stanley, and Dr. Satheesh Babu T. G., “Paper Based Microfluidic Device for the Detection of Total Protein in Blood”, Materials Today: Proceedings, vol. 5, pp. 16220 - 16225, 2018.