Useful contacts: A new method to achieve regular patterns generates anisotropic, “patchy” microspheres by using interfacial condensation of a liquid mask and the proximity of the particles to their neighbors to determine a mask pattern. The microspheres are separated from the scaffold and labeled with a first protein at non-mask regions (green) followed by removal of the mask and immobilization of a second protein (red).
Dr. Kaladhar Kamalasanan, Jhunjhunwala, S., Wu, J., Swanson, A., Gao, D., and Little, S. R., “Patchy, Anisotropic Microspheres with Soft Protein Islets”, Angewandte Chemie International Edition, vol. 50, no. 37, pp. 8706–8708, 2011.