Rasashastra is one of the subjects in Ayurveda which specially deals with minerals, herbal and herbo-mineral preparations along with their therapeutic uses and is known for its quick action and has been proved to be effective in treating various ailments. Malla Yoga is a preparation mentioned in Sidhabheshaja manimala Swasa adhikara 4/8, which contains Shodhita Shankha and Shoditha Malla as its main ingredients. This article points towards pharmaceutical study, physico-chemical study, analytical study and acute toxicity study of Malla yoga. The study was done for 14 days in Albino rats to find out the minimum therapeutic dose, maximum tolerated dose and median lethal dose
(LD50 value) and toxic effect in the organ system. Thus this paper highlights the importance of toxicity study of a drug before administration to prove its safety profile, acute toxicity and pharmaceutical study of Malla yoga and its efficacy to cure various disorders whose incidence has been increasing tremendously in the present world with begrimed surroundings.
P. K. Vineeth and Rajalakshmi, S., “Pharmaceutico – Analytical study of Malla Yoga W.S.R. to its Toxicity study in Rats”, Anveshana Ayurveda Medical Journal, vol. 1, no. 5, 2015.