We developed novel β-chitin/nanosilver composite scaffolds for wound healing applications using β-chitin hydrogel with silver nanoparticles. The prepared nanosilver particles and nanocomposite scaffolds were characterized using SEM, FT-IR, XRD and TGA studies. The antibacterial, blood-clotting, swelling, cell attachment and cytotoxicity studies of the prepared composite scaffolds were evaluated. The prepared β-chitin/nanosilver composite scaffolds were bactericidal against Escherichia coli and Staphylococcus aureus and it showed good blood-clotting ability as well. Cell attachment studies using vero (epithelial) cells showed that the cells were well attached on the scaffolds. These results suggested that β-chitin/nanosilver composite scaffold could be a promising candidate for wound dressing applications. © 2009 Elsevier Ltd. All rights reserved.
cited By (since 1996)54
P. T. Sa Kumar, Abhilash, Sa, Manzoor, Ka, Nair, S. Va, Tamura, Hb, and Jayakumar, Ra, “Preparation and characterization of novel β-chitin/nanosilver composite scaffolds for wound dressing applications”, Carbohydrate Polymers, vol. 80, pp. 761-767, 2010.