Publication Type:

Journal Article

Source:

Carbohydrate Polymers, Volume 76, Number 2, p.255 - 260 (2009)

URL:

http://www.sciencedirect.com/science/article/pii/S0144861708004852

Keywords:

Chitosan hydrogel, Chitosan/gelatin membranes, Mechanical properties, Thermal studies, XRD studies

Abstract:

Chitin and chitosan are novel biomaterials. The novel chitosan/gelatin membranes were prepared using the suspension of chitosan hydrogel mixed with gelatin. The prepared chitosan/gelatin membranes were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), mechanical, swelling, and thermal studies. The morphology of these chitosan/gelatin membranes was found to be very smooth and homogeneous. The XRD studies showed that the chitosan/gelatin membranes have good compatibility and interaction between the chitosan and gelatin. The stress and elongation of chitosan/gelatin membranes on wet condition showed excellent when the mixture ratio of gelatin was 0.50. The prepared chitosan/gelatin membranes showed good swelling, mechanical and thermal properties. Cell adhesion studies were also carried out using human MG-63 osteoblast-like cells. The cells incubated with chitosan/gelatin membranes for 24h were capable of forming cell adhesion. Thus the prepared chitosan/gelatin membranes are bioactive and are suitable for cell adhesion suggesting that these membranes can be used for tissue-engineering applications. Therefore, these novel chitosan/gelatin membranes are useful for biomedical applications

Cite this Research Publication

H. Nagahama, Maeda, H., Kashiki, T., Dr. Jayakumar Rangasamy, Furuike, T., and Tamura, H., “Preparation and Characterization of Novel Chitosan/gelatin Membranes Using Chitosan Hydrogel”, Carbohydrate Polymers, vol. 76, pp. 255 - 260, 2009.