Effective anticoagulation is critical in patients with prosthetic heart valve [PHV], but remains challenging in pregnancy because both oral anticoagulation and heparin are associated with important fetal and maternal risks. Herein we report a case of 23-year-old pregnant woman presented with PHV thrombosis during late second trimester and complicated by Immune mediated thrombocytopenia.She underwent Redo MVR [25mm CE Perimount Plus Pericardial Bioprosthetic valve] + LSCS. Peri operatively she was managed with Platelet transfusions/ Immunoglobulins/ Steroid pulse therapy and recovered well.
Rajesh Jose, Dr. Praveen Varma, and Agarwal, G., “Prosthetic heart valve thrombosis in pregnancy”, Kerala Heart Journal, vol. 6, no. 2, 2016.