Publication Type:

Journal Article


Iranian Journal of Nuclear Medicine, Tehran University of Medical Sciences, Volume 22, Number 2, p.94-97 (2014)



adult, antineoplastic agent, article, bone metastasis, buccal mucosa squamous cell carcinoma, cancer recurrence, case report, cheek mucosa, chemoradiotherapy, computer assisted emission tomography, contrast enhancement, echocardiography, fluorodeoxyglucose f 18, free tissue graft, heart metastasis, human, Indian, interventricular septum metastasis, lung metastasis, lymph node metastasis, male, mandible resection, maxilla resection, mouth squamous cell carcinoma, neck dissection, tongue carcinoma, whole body CT, wide excision


Metastatic tumors to the heart unlike primary cardiac tumors are not rare. Despite its frequency, cardiac metastasis is commonly detected only during autopsy as the symptoms of disseminated metastasis prevail over symptoms caused by cardiac metastasis and hence is overlooked most of the time. Tumors more commonly found metastasizing to the heart are malignancies of lung, breast, esophagus, lymphoma, leukemia, and malignant melanoma. Head and neck malignancies have a lower incidence of distant metastasis when compared to other malignancies and it rarely causes cardiac metastasis. Here we report the case of a 32 year old Indian male with squamous cell carcinoma of buccal mucosa who underwent surgery followed by chemoradiation. Follow up, FDG PET-CT showed extensive lymphnodal, pulmonary & skeletal metastasis apart from local recurrence in the tongue and floor of mouth. Another discrete foci of increased FDG uptake was noted in the region of heart which corresponded to a hypodense foci in the interventricular septum in contrast enhanced CT raising the possibility of cardiac metastasis. Subsequently, 2D echocardiogram with parasternal long axis view showed hyperdense anterior septum with speckled appearance with a hyperechoic structure attached to the septum towards the right ventricular side confirming metastatic deposit to the heart.


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Cite this Research Publication

G. S. Shagos, Padma, S., P. Sundaram, S., and Tewari, A., “Rare case of squamous cell carcinoma of buccal mucosa metastasizing to interventricular septum in a young adult detected by18F-FDG PET-CT”, Iranian Journal of Nuclear Medicine, vol. 22, pp. 94-97, 2014.