Publication Type:

Journal Article


Medical Hypotheses, Volume 77, Number 3, p.460-461 (2011)



antidiabetic agent, article, diabetes mellitus, diet, ethnicity, genetic variability, Genetic Variation, Glucose, glucose metabolism, human, Humans, insulin, insulin aspart, insulin glargine, insulin resistance, Insulins, medical society, non insulin dependent diabetes mellitus, practice guideline, Practice Guidelines as Topic, Type 2


Even in a developed country like USA, substantial number of subjects with type 2 diabetes fail to achieve adequate glycemic control despite the availability of several groups of anti-diabetic medications targeting multiple pathophysiological features of type 2 diabetes. Are we treating our type 2 diabetes subjects appropriately? To aid practicing clinicians various professional bodies like American Diabetes Association (ADA), European Association for Study of Diabetes (EASD), Canadian Diabetes Association (CDA), etc. regularly publish clinical practice guidelines and consensus statements. Since racial and ethnic differences in insulin resistance, dietary pattern, glucose metabolism, genetic variation are known phenomena, it would be interesting to evaluate the aptness of these guidelines from ethnopharmacy perspective. We postulate that certain ethnic characteristics of populations will decide the best form of insulin therapy rather than blanket recommendations on starting every patient on basal insulin. © 2011 Elsevier Ltd.


cited By (since 1996)2

Cite this Research Publication

Ma John, Kalra, Sb, Unnikrishnan, A. Gc, Ganapathy, Bd, Baruah, M. Pe, and Sahay, R. Kf, “Recommendations for insulin initiation based on ethnicity”, Medical Hypotheses, vol. 77, pp. 460-461, 2011.