A cellular responsive, highly selective fluorogenic and chromogenic chemodosimeter probe for HNO is developed. This new probe showed ∼30 fold fluorescence enhancement in the presence of HNO and is sensitive to HNO at concentrations as low as 0.02 μM. Further, it is capable of detecting HNO levels in cellular milieus as well as in live specimens e.g. C. elegans.
K. N. Bobba, Zhou, Y., Guo, L. E., Zang, T. N., Zhang, J. F., and Bhuniya, S., “Resorufin based fluorescent “turn-on” chemodosimeter for nitrosyl (HNO)”, RSC Advances - An international journal to further the chemical sciences, 2015.