<p>We have synthesized (S)-(+)-ibuprofen-based hydrogelators that feature dipeptide linkages. In aqueous media, one of these hydrogelators formed robust gels that were stable for several months. Enzyme-mediated hydrolysis offers a route toward the sustained release of this anti-inflammatory agent.</p>
S. Bhuniya, Seo, Y. Jun, and Kim, B. Hyean, “(S)-(+)-Ibuprofen-based hydrogelators: an approach toward anti-inflammatory drug delivery”, Tetrahedron Letters, vol. 47, pp. 7153 - 7156, 2006.