Publication Type:

Journal Article

Source:

Annals of Tropical Medicine and Public Health, Volume 5, Number 4, p.286-290 (2012)

URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84870267217&partnerID=40&md5=a5de364b3b033f04691e518e001e645e

Keywords:

adult, aged, article, child, clinical article, clinical feature, demography, dengue, female, human, India, leptospirosis, male, medical record review, mixed infection, morbidity, mortality, prevalence, school child, serodiagnosis, symptom

Abstract:

Background: Concurrent epidemics of both dengue fever and leptospirosis are known to occur in the tropics; however, it is unclear whether coinfection is associated with different clinical manifestations and outcomes. Materials and Methods: Medical records for patients with serological evidence of leptospirosis, dengue, and coinfection from January 2007 to December 2008 were abstracted using a standardized abstraction form. The patients' demographic data, underlying diseases, clinical manifestations, laboratory data, and disease outcomes were retrospectively analyzed. Results: The frequency of leptospirosis was 15.8% (287/1814), while that of dengue was 14.8% (239/1610) and coinfection was seen in 1.3% (17/1309). Highest mortality of 29.6% (5/17) was seen in coinfected cases, followed by leptospirosis (14.6%) and dengue (3.7%). Conclusion: In the tropics, leptospirosis and dengue can coexist and increased awareness of coinfection, and an enhanced ability to diagnose it early in illness, will help guide the appropriate use antibiotics and supportive measures to reduce mortality.

Notes:

cited By (since 1996)0

Cite this Research Publication

Aa Kumar, Balachandran, Va, Dominic, Aa, Dinesh, Ka, Karim, Sa, and Rao, Gb, “Serological evidence of leptospirosis and dengue coinfection in an endemic region in South India”, Annals of Tropical Medicine and Public Health, vol. 5, pp. 286-290, 2012.

207
PROGRAMS
OFFERED
5
AMRITA
CAMPUSES
15
CONSTITUENT
SCHOOLS
A
GRADE BY
NAAC, MHRD
8th
RANK(INDIA):
NIRF 2018
150+
INTERNATIONAL
PARTNERS