Embelin, a naturally occurring compound extracted from Embelia ribes is used in Ayurvedic system of medicine owing to its wide spectrum of biological activities. In the present work, we have aimed at improving the efficacy of Embelin by appropriate structural modifications. A few novel derivatives of Embelin have been prepared. The antibacterial screening of these derivatives were carried out and compared with a well known antibiotic, Streptomycin. The derivatives exhibited better activity than Streptomycin and the lead molecule, Embelin.
Subramanian L, Leema M, Pradeep N S, Joy B, and Dr. Zeena S. Pillai, “Synthesis and Antibacterial Screening of Novel Derivatives of Embelin”, in International Conference on Advances in Materials and Manufacturing Applications 2017 IConAMMA 2017 - IOP Conference Series: Materials Science and Engineering, 2018, 1st ed., vol. 310.