A practical synthesis of polyhydroxy- and regiospecifically methylated flavone-3-ols which are components of commercial â€˜seabuckthorn flavoneâ€™ has been achieved by modified Algarâ€“Flynnâ€“Oyamada method. Antioxidant activities of seabuckthorn extracts, isolated products and a number of flavone-3-ols have been determined. Structureâ€“activity relationships have been discussed. Amongst the compounds tested, gallic acid, which is also present in seabuckthorn, was found to be the most effective antioxidant and radioprotectant.
cited By (since 1996)3
Pandurangan Nanjan, Chinchu Bose, and A. Banerji, “Synthesis and Antioxygenic Activities of Seabuckthorn Flavone-3-ols and Analogs”, Bioorganic & Medicinal Chemistry Letters, vol. 21, pp. 5328 - 5330, 2011.