Publication Type:

Journal Article

Source:

Carbohydrate Polymers, Volume 87, Number 1, p.943 - 949 (2012)

URL:

http://www.sciencedirect.com/science/article/pii/S0144861711007284

Keywords:

Chitin nanogels, Drug delivery, swelling, tissue engineering

Abstract:

Abstract In this work we developed biodegradable chitin nanogels (CNGs) of size 65nm by controlled regeneration method and characterized. The CNGs showed higher swelling and degradation in acidic pH. The in vitro cytocompatibility was analyzed on an array of cell lines and cell uptake studies were done by conjugating CNGs with the rhodamine-123 dye (rhodamine-123–CNGs), which showed retention of nanogels inside the cells. Our preliminary studies reveal that these nanogels could be useful for the delivery of drugs, growth factors for drug delivery and tissue engineering.

Notes:

cited By 17

Cite this Research Publication

S. N. Rejinold, Nair, A., Dr. Sabitha M., Chennazhi, K. P., Tamura, H., Nair, S. V., and Dr. Jayakumar Rangasamy, “Synthesis, Characterization and in vitro Cytocompatibility Studies of Chitin Nanogels for Biomedical Applications”, Carbohydrate Polymers, vol. 87, pp. 943 - 949, 2012.

207
PROGRAMS
OFFERED
6
AMRITA
CAMPUSES
15
CONSTITUENT
SCHOOLS
A
GRADE BY
NAAC, MHRD
8th
RANK(INDIA):
NIRF 2018
150+
INTERNATIONAL
PARTNERS