<p>The present invention relates to a photosensitizer-containing nanoparticle, comprising a photosensitizer covalently bonded throughout at least a part of said nanoparticle to the nanoparticle matrix material and incorporated therein in a quasi-aggregated state. The present invention further relates to methods for producing the invention nanoparticles, and to methods of killing cancer cells by PDT treatment using the said nanoparticles.</p>
M. Koyakutty, Robinson, D. J., Sterenborg, H. J. C. M., Kascakova, S., and Shantikumar V Nair, “Targeted nano-photomedicines for photodynamic therapy of cancer”, U.S. Patent EP200907881932012.