Differentiated thyroid cancer may coexist with hyperthyroidism. Cancer cell mass is less functional and appears as cold nodule in thyroid scintigraphy. Cancer cell mass rarely becomes site of excess hormone production. When thyroid cancer cell mass occupies a scintigraphically hot, functionally autonomous thyroid nodule and if thyrotoxicosis is attributable exclusively to this nodule, as shown by clinical and histologic correlation, a toxic thyroid carcinoma is diagnosed. We are reporting case feature which coincides well with the above mentioned diagnosis.
Misha J. C. Babu, C Nair, G., Riju R. Menon, and Pradeep Jacob, “Toxic thyroid carcinoma: A new case.”, Indian Journal of Endocrinology and Metabolism, vol. 16, no. 4, pp. 668–670, 2012.